Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA001531-05S1
Application #
3206940
Study Section
(DABA)
Project Start
1985-09-30
Project End
1988-08-31
Budget Start
1986-09-01
Budget End
1987-08-31
Support Year
5
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Xu, X; Domino, E F (1994) Phencyclidine-induced behavioral sensitization. Pharmacol Biochem Behav 47:603-8
Xu, X; Domino, E F (1994) Asymmetric cross-sensitization to the locomotor stimulant effects of phencyclidine and MK-801. Neurochem Int 25:155-9
Holsztynska, E J; Weber, W W; Domino, E F (1991) Genetic polymorphism of cytochrome P-450-dependent phencyclidine hydroxylation in mice. Comparison of phencyclidine hydroxylation in humans. Drug Metab Dispos 19:48-53
Pohorecki, R; Rayburn, W; Coon, W W et al. (1989) Some factors affecting phencyclidine biotransformation by human liver and placenta. Drug Metab Dispos 17:271-4
Gole, D J; Pirat, J L; Kamenka, J M et al. (1988) Hydroxy metabolites of phencyclidine. Identification and quantitation of two novel metabolites. Drug Metab Dispos 16:386-91
Domino, E F; Gole, D; Koek, W (1987) Metaphit, a proposed phencyclidine receptor acylator: disruption of mouse motor behavior and absence of PCP antagonist activity. J Pharmacol Exp Ther 243:95-100
Holsztynska, E J; Domino, E F (1986) Quantitation of phencyclidine, its metabolites, and derivatives by gas chromatography with nitrogen-phosphorus detection: application for in vivo and in vitro biotransformation studies. J Anal Toxicol 10:107-15
Lal, J; Krutak-Krol, H; Domino, E F (1986) Comparative antitussive effects of dextrorphan, dextromethorphan and phencyclidine. Arzneimittelforschung 36:1075-8
Domino, E F (1986) Comparison of phencyclidine and related substances with various indole, phenethylamine, and other psychotomimetics. Psychopharmacol Bull 22:973-6
Holsztynska, E J; Domino, E F (1985) Biotransformation of phencyclidine. Drug Metab Rev 16:285-320