Locus Coeruleus Activity and Opiate Discrimination

Valentino, Rita

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Drug Abuse (NIDA)
• Type: Research Project (R01)
• Project #: 5R01DA003695-02
• Application #: 3208272
• Study Section: (DABA)
• Project Start: 1985-04-01
• Project End: 1988-03-31
• Budget Start: 1986-04-01
• Budget End: 1987-03-31
• Support Year: 2
• Fiscal Year: 1986

Institution

• Name: George Washington University
• Type: Schools of Medicine
• City: Washington
• State: DC
• Country: United States
• Zip Code: 20052

Publications

Valentino, R J; Wehby, R G (1989) Locus ceruleus discharge characteristics of morphine-dependent rats: effects of naltrexone. Brain Res 488:126-34

Valentino, R J; Wehby, R G (1988) Corticotropin-releasing factor: evidence for a neurotransmitter role in the locus ceruleus during hemodynamic stress. Neuroendocrinology 48:674-7

Valentino, R J; Foote, S L (1988) Corticotropin-releasing hormone increases tonic but not sensory-evoked activity of noradrenergic locus coeruleus neurons in unanesthetized rats. J Neurosci 8:1016-25

Valentino, R J; Wehby, R G (1988) Morphine effects on locus ceruleus neurons are dependent on the state of arousal and availability of external stimuli: studies in anesthetized and unanesthetized rats. J Pharmacol Exp Ther 244:1178-86

Valentino, R J; Aulisi, E F (1987) Carbachol-induced increases in locus coeruleus spontaneous activity are associated with an altered pattern of response to sensory stimuli. Neurosci Lett 74:297-303