Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA004141-02
Application #
3209365
Study Section
Pharmacology I Research Subcommittee (DABR)
Project Start
1987-05-01
Project End
1990-04-30
Budget Start
1988-06-01
Budget End
1989-04-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
University of South Florida
Department
Type
Schools of Medicine
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612

  Publications

Ongradi, J; Specter, S; Horvath, A et al. (1999) [Additive effect of marihuana and retrovirus in the anergy of natural killer cells in mice] Orv Hetil 140:81-4
Ongradi, J; Specter, S; Horvath, A et al. (1998) Combined in vitro effect of marijuana and retrovirus on the activity of mouse natural killer cells. Pathol Oncol Res 4:191-9
Zheng, Z M; Specter, S C (1996) Delta-9-tetrahydrocannabinol suppresses tumor necrosis factor alpha maturation and secretion but not its transcription in mouse macrophages. Int J Immunopharmacol 18:53-68
Zheng, Z M; Specter, S (1996) Dynamic production of tumour necrosis factor-alpha (TNF-alpha) messenger RNA, intracellular and extracellular TNF-alpha by murine macrophages and possible association with protein tyrosine phosphorylation of STAT1 alpha and ERK2 as an early signal. Immunology 87:544-50
Zheng, Z M; Specter, S (1996) Delta-9-tetrahydrocannabinol: an inhibitor of STAT1 alpha protein tyrosine phosphorylation. Biochem Pharmacol 51:967-73
Zheng, Z M; Specter, S C; Lancz, G (1995) Bovine serum albumin preparations enhance in vitro production of tumor necrosis factor alpha by murine macrophages. Immunol Invest 24:737-56
Zheng, Z M; Specter, S (1994) Suppression by delta-9-tetrahydrocannabinol of lipopolysaccharide-induced and intrinsic tyrosine phosphorylation and protein expression in mouse peritoneal macrophages. Biochem Pharmacol 47:2243-52
Diaz, S; Specter, S; Vanderhoek, J Y et al. (1994) The effect of delta-9-tetrahydrocannabinol on arachidonic acid metabolism in human peripheral blood mononuclear cells. J Pharmacol Exp Ther 268:1289-96
Trisler, K; Specter, S (1994) Delta-9-tetrahydrocannabinol treatment results in a suppression of interleukin-2-induced cellular activities in human and murine lymphocytes. Int J Immunopharmacol 16:593-603
Diaz, S; Specter, S; Coffey, R G (1993) Suppression of lymphocyte adenosine 3':5'-cyclic monophosphate (cAMP) by delta-9-tetrahydrocannabinol. Int J Immunopharmacol 15:523-32

Showing the most recent 10 out of 22 publications