Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA012366-03
Application #
6378862
Study Section
Special Emphasis Panel (ZRG1-AARR-5 (01))
Program Officer
Khalsa, Jagjitsingh H
Project Start
1999-08-15
Project End
2004-07-31
Budget Start
2001-08-01
Budget End
2002-07-31
Support Year
3
Fiscal Year
2001
Total Cost
$242,434
Indirect Cost
Name
State University of New York at Buffalo
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Nair, Madhavan P N; Samikkannu, Thangavel (2012) Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine. Curr HIV Res 10:429-34
Agudelo, Marisela; Gandhi, Nimisha; Saiyed, Zainulabedin et al. (2011) Effects of alcohol on histone deacetylase 2 (HDAC2) and the neuroprotective role of trichostatin A (TSA). Alcohol Clin Exp Res 35:1550-6
Nair, Madhavan P N; Saiyed, Zainulabedin M (2011) Effect of methamphetamine on expression of HIV coreceptors and CC-chemokines by dendritic cells. Life Sci 88:987-94
Samikkannu, Thangavel; Agudelo, Marisela; Gandhi, Nimisha et al. (2011) Human immunodeficiency virus type 1 clade B and C gp120 differentially induce neurotoxin arachidonic acid in human astrocytes: implications for neuroAIDS. J Neurovirol 17:230-8
Samikkannu, Thangavel; Rao, Kurapati V K; Gandhi, Nimisha et al. (2010) Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDS. J Neurovirol 16:255-63
Boukli, Nawal M; Saiyed, Zainulabedin M; Ricaurte, Martha et al. (2010) Implications of ER stress, the unfolded protein response, and pro- and anti-apoptotic protein fingerprints in human monocyte-derived dendritic cells treated with alcohol. Alcohol Clin Exp Res 34:2081-8
Gandhi, Nimisha; Saiyed, Zainulabedin M; Napuri, Jessica et al. (2010) Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood-brain barrier dysfunction: implications for HIV-1-associated neurocognitive disorder. J Neurovirol 16:294-305
Babu, Dakshayani Kadiyala; Diaz, Alain; Samikkannu, Thangavel et al. (2009) Upregulation of serotonin transporter by alcohol in human dendritic cells: possible implication in neuroimmune deregulation. Alcohol Clin Exp Res 33:1731-8
Gandhi, Nimisha; Saiyed, Zainulabedin; Thangavel, Samikkannu et al. (2009) Differential effects of HIV type 1 clade B and clade C Tat protein on expression of proinflammatory and antiinflammatory cytokines by primary monocytes. AIDS Res Hum Retroviruses 25:691-9
Samikkannu, Thangavel; Saiyed, Zainulabedin M; Rao, K V K et al. (2009) Differential regulation of indoleamine-2,3-dioxygenase (IDO) by HIV type 1 clade B and C Tat protein. AIDS Res Hum Retroviruses 25:329-35

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