Auditory scene analysis, the ability to parse and organize the mixture of incoming sounds to coherent streams of information, is a fundamental process of the auditory system that allows us to follow a single voice in the midst of a crowded room or to listen to the melody of the flute within an orchestral suite. Accurate speech perception relies on the ability to discriminate and segregate sound elements in the acoustic signal. Despite the importance of this process for human behavior, the neural mechanisms that subserve the organization of the auditory input are poorly understood. The long term goal of the project is to understand how the human brain organizes acoustic input into meaningful auditory objects. The experiments proposed are aimed at evaluating the processing stages between sensory input and behavioral response by specifying the relationship between the stimulus-driven and attentive mechanisms that give rise to the perception of a coherent auditory environment. This will be accomplished using high temporal resolution of event-related potentials (ERPs) in conjunction with behavioral methods to compare the outcome of stimulus-driven auditory processes with the perception resulting from attentive processing of the same sounds across various experimental conditions. The results of the proposed experiments will provide new insights into the processes involved in perceiving complex auditory scenes and lead to a greater understanding of the contribution of automatic and attentional mechanisms underlying both normal and impaired auditory perception. Deficits in central auditory processing are thought to play a key role in many cognitive disorders (e.g., autism, dyslexia). Using electrophysiological measures, in conjunction with behavioral methods to understand how stimulus-driven processes and attention interact in perception will advance our understanding of impaired processing, which is essential for developing diagnostic strategies and rehabilitative treatments. Since subject response is not needed for obtaining certain ERPs, this methodological approach is advantageous for use with children and impaired populations for whom task requirements may be difficult, and thus has the potential to be an important non-invasive tool for diagnosis and assessment of central auditory processing deficits.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC004263-10
Application #
8048101
Study Section
Cognition and Perception Study Section (CP)
Program Officer
Donahue, Amy
Project Start
1999-12-01
Project End
2012-09-12
Budget Start
2011-04-01
Budget End
2012-09-12
Support Year
10
Fiscal Year
2011
Total Cost
$333,653
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Neurosciences
Type
Schools of Medicine
DUNS #
110521739
City
Bronx
State
NY
Country
United States
Zip Code
10461
Yu, Yan H; Shafer, Valerie L; Sussman, Elyse S (2018) The Duration of Auditory Sensory Memory for Vowel Processing: Neurophysiological and Behavioral Measures. Front Psychol 9:335
Ruhnau, Philipp; Schröger, Erich; Sussman, Elyse S (2017) Implicit expectations influence target detection in children and adults. Dev Sci 20:
Symonds, Renée M; Lee, Wei Wei; Kohn, Adam et al. (2017) Distinguishing Neural Adaptation and Predictive Coding Hypotheses in Auditory Change Detection. Brain Topogr 30:136-148
Costa-Faidella, Jordi; Sussman, Elyse S; Escera, Carles (2017) Selective entrainment of brain oscillations drives auditory perceptual organization. Neuroimage 159:195-206
Dinces, Elizabeth; Sussman, Elyse S (2017) Attentional Resources Are Needed for Auditory Stream Segregation in Aging. Front Aging Neurosci 9:414
Rota-Donahue, Christine; Schwartz, Richard G; Shafer, Valerie et al. (2016) Perception of Small Frequency Differences in Children with Auditory Processing Disorder or Specific Language Impairment. J Am Acad Audiol 27:489-97
Rankin, James; Sussman, Elyse; Rinzel, John (2015) Neuromechanistic Model of Auditory Bistability. PLoS Comput Biol 11:e1004555
Hisagi, Miwako; Shafer, Valerie L; Strange, Winifred et al. (2015) Neural measures of a Japanese consonant length discrimination by Japanese and American English listeners: Effects of attention. Brain Res 1626:218-31
Rimmele, Johanna Maria; Sussman, Elyse; Poeppel, David (2015) The role of temporal structure in the investigation of sensory memory, auditory scene analysis, and speech perception: a healthy-aging perspective. Int J Psychophysiol 95:175-83
Max, Caroline; Widmann, Andreas; Schröger, Erich et al. (2015) Effects of explicit knowledge and predictability on auditory distraction and target performance. Int J Psychophysiol 98:174-81

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