Abstract

This proposal seeks to develop a clinically useful artificial oral mucosa. Covering epithelial and connective tissue defects in the oral cavity is a problem, in preprosthetic, periodontal, and cancer surgery, in which special demands are made on the function and quality of the graft. Current methods of providing mucosal substitutes are inadequate. A recently developed collagen-glycosaminoglycan membrane will be tested as an artificial mucosa. Results will be evaluated using histologic and wound size determinations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE007086-02
Application #
3220623
Study Section
Oral Biology and Medicine Study Section (OBM)
Project Start
1985-09-01
Project End
1988-08-31
Budget Start
1986-09-01
Budget End
1987-08-31
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199