Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
3R01DE009830-03S1
Application #
2130758
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1992-06-01
Project End
1995-05-31
Budget Start
1994-06-01
Budget End
1996-05-31
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Agarwal, S; Chandra, C S; Piesco, N P et al. (1998) Regulation of periodontal ligament cell functions by interleukin-1beta. Infect Immun 66:932-7
Brady, T A; Piesco, N P; Buckley, M J et al. (1998) Autoregulation of periodontal ligament cell phenotype and functions by transforming growth factor-beta1. J Dent Res 77:1779-90
Agarwal, S; Piesco, N P; Johns, L P et al. (1995) Differential expression of IL-1 beta, TNF-alpha, IL-6, and IL-8 in human monocytes in response to lipopolysaccharides from different microbes. J Dent Res 74:1057-65
Quintero, J C; Piesco, N P; Langkamp, H H et al. (1995) LPS responsiveness in periodontal ligament cells is regulated by tumor necrosis factor-alpha. J Dent Res 74:1802-11
Agarwal, S; Baran, C; Piesco, N P et al. (1995) Synthesis of proinflammatory cytokines by human gingival fibroblasts in response to lipopolysaccharides and interleukin-1 beta. J Periodontal Res 30:382-9
Agarwal, S; Suzuki, J B; Riccelli, A E (1994) Role of cytokines in the modulation of neutrophil chemotaxis in localized juvenile periodontitis. J Periodontal Res 29:127-37
Agarwal, S; Suzuki, J B; Piesco, N P et al. (1994) Neutrophil function in juvenile periodontitis: induction of adherence. Oral Microbiol Immunol 9:262-71
Agarwal, S; Piesco, N P (1994) Poly ADP-ribosylation of a 90-kDa protein is involved in TNF-alpha-mediated cytotoxicity. J Immunol 153:473-81