Molecular Mechanisms of Insulin & Glycogen Synthase

Soderling, Thomas R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 7R01DK017808-17
• Application #: 3225875
• Study Section: Biochemistry Study Section (BIO)
• Project Start: 1978-07-01
• Project End: 1993-06-30
• Budget Start: 1991-03-01
• Budget End: 1991-06-30
• Support Year: 17
• Fiscal Year: 1990

Institution

• Name: Oregon Health and Science University
• Type: Organized Research Units
• DUNS #: 009584210
• City: Portland
• State: OR
• Country: United States
• Zip Code: 97239

Publications

Perrino, B A; Ng, L Y; Soderling, T R (1995) Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domain. J Biol Chem 270:340-6

Filipek, A; Soderling, T R (1993) Identification of an autoinhibitory domain in the insulin receptor tyrosine kinase. Mol Cell Biochem 120:103-10

Shibata, H; Robinson, F W; Soderling, T R et al. (1991) Effects of okadaic acid on insulin-sensitive cAMP phosphodiesterase in rat adipocytes. Evidence that insulin may stimulate the enzyme by phosphorylation. J Biol Chem 266:17948-53

Brickey, D A; Colbran, R J; Fong, Y L et al. (1990) Expression and characterization of the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II using the baculovirus expression system. Biochem Biophys Res Commun 173:578-84

Yang, S D; Chang, S Y; Soderling, T R (1987) Characterization of an autophosphorylation-dependent multifunctional protein kinase from liver. J Biol Chem 262:9421-7