Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
7R01DK035182-04
Application #
3233455
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1987-09-01
Project End
1989-03-31
Budget Start
1987-09-01
Budget End
1989-03-31
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Fox, C C; Lichtenstein, L M; Roche, J K (1993) Intestinal mast cell responses in idiopathic inflammatory bowel disease. Histamine release from human intestinal mast cells in response to gut epithelial proteins. Dig Dis Sci 38:1105-12
Roche, J K; Crum, C P (1991) Local immunity and the uterine cervix: implications for cancer-associated viruses. Cancer Immunol Immunother 33:203-9
Gardner, A L; Roche, J K; Weikel, C S et al. (1991) Intestinal cryptosporidiosis: pathophysiologic alterations and specific cellular and humoral immune responses in rnu/+ and rnu/rnu (athymic) rats. Am J Trop Med Hyg 44:49-62
Snyder, K A; Barber, S R; Symbula, M et al. (1991) Binding by immunoglobulin to the HPV-16-derived proteins L1 and E4 in cervical secretions of women with HPV-related cervical disease. Cancer Res 51:4423-9
Crum, C P; Barber, S; Symbula, M et al. (1990) Coexpression of the human papillomavirus type 16 E4 and L1 open reading frames in early cervical neoplasia. Virology 178:238-46
Winter, H S; Crum Jr, P M; King, N W et al. (1989) Expression of immune sensitization to epithelial cell-associated components in the cotton-top tamarin: a model of chronic ulcerative colitis. Gastroenterology 97:1075-82
Fiocchi, C; Roche, J K; Michener, W M (1989) High prevalence of antibodies to intestinal epithelial antigens in patients with inflammatory bowel disease and their relatives. Ann Intern Med 110:786-94
Smith, K N; Paul, J W; Roche, J K (1988) Induction by cells of immune responses to intestinal epithelial cell-associated components (ECAC): transfer with cultured murine mesenteric and popliteal/axillary lymph node cells. Cell Immunol 113:290-307