Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK035187-11
Application #
2139519
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1985-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Biochemistry
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Lee, S Y; Klevit, R E (2000) The whole is not the simple sum of its parts in calmodulin from S. cerevisiae. Biochemistry 39:4225-30
Rohl, C A; Boeckman, F A; Baker, C et al. (1999) Solution structure of the sodium channel inactivation gate. Biochemistry 38:855-61
Rajagopal, P; Jones, B E; Klevit, R E (1998) Solvent exchange rates of side-chain amide protons in proteins. J Biomol NMR 11:205-12
Rajagopal, P; Waygood, E B; Reizer, J et al. (1997) Demonstration of protein-protein interaction specificity by NMR chemical shift mapping. Protein Sci 6:2624-7
Jones, B E; Rajagopal, P; Klevit, R E (1997) Phosphorylation on histidine is accompanied by localized structural changes in the phosphocarrier protein, HPr from Bacillus subtilis. Protein Sci 6:2107-19
Jones, B E; Dossonnet, V; Kuster, E et al. (1997) Binding of the catabolite repressor protein CcpA to its DNA target is regulated by phosphorylation of its corepressor HPr. J Biol Chem 272:26530-5
Thapar, R; Nicholson, E M; Rajagopal, P et al. (1996) Influence of N-cap mutations on the structure and stability of Escherichia coli HPr. Biochemistry 35:11268-77
Peterkofsky, A; Seok, Y J; Amin, N et al. (1995) The Escherichia coli adenylyl cyclase complex: requirement of PTS proteins for stimulation by nucleotides. Biochemistry 34:8950-9
Pullen, K; Rajagopal, P; Branchini, B R et al. (1995) Phosphorylation of serine-46 in HPr, a key regulatory protein in bacteria, results in stabilization of its solution structure. Protein Sci 4:2478-86
Herzberg, O; Klevit, R (1994) Unraveling a bacterial hexose transport pathway. Curr Opin Struct Biol 4:814-22

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