This project involves the study of erythropoietin-responsive cells, cells that respond to colonystimulating factor, pluripotent hematopoietic stem cells, and the interrelationships among them. Our working hypothesis is that these are essentially the same cells and can be defined by the presence or absence of receptors for the inducers of hematopoietic cell differentiation. We are studying the properties of the erythropoietin receptor of mouse cells and the role of interleukin-3 on the regulation of response to erythropoietin. (M)

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK040250-17
Application #
3240410
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1988-05-01
Project End
1993-04-30
Budget Start
1991-05-01
Budget End
1992-04-30
Support Year
17
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637