Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK043159-03
Application #
3244488
Study Section
Biochemistry Study Section (BIO)
Project Start
1990-02-16
Project End
1994-01-31
Budget Start
1992-02-01
Budget End
1994-01-31
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Gorski, N P; Nouraldin, H; Dube, D M et al. (1996) Reduced fatty acid ethyl ester synthase activity in the white blood cells of alcoholics. Alcohol Clin Exp Res 20:268-74
Rossetti, R G; Seiler, C M; Laposata, M et al. (1995) Differential regulation of human T lymphocyte protein kinase C activity by unsaturated fatty acids. Clin Immunol Immunopathol 76:220-4
Laposata, M; Szczepiorkowski, Z M; Brown, J E (1995) Fatty acid ethyl esters: non-oxidative metabolites of ethanol. Prostaglandins Leukot Essent Fatty Acids 52:87-91
Teruya, J; Cluette-Brown, J; Szczepiorkowski, Z M et al. (1995) Mode of transport of fatty acid to endothelial cells influences intracellular fatty acid metabolism. J Lipid Res 36:266-76
Bird, D A; Szczepiorkowski, Z M; Trace, V C et al. (1995) Low-density lipoprotein reconstituted with fatty acid ethyl esters as a physiological vehicle for ethyl ester delivery to intact cells. Alcohol Clin Exp Res 19:1265-70
Doyle, K M; Bird, D A; al-Salihi, S et al. (1994) Fatty acid ethyl esters are present in human serum after ethanol ingestion. J Lipid Res 35:428-37
Hallaq, Y; Becker, T C; Manno, C S et al. (1993) Use of acetyl chloride/methanol for assumed selective methylation of plasma nonesterified fatty acids results in significant methylation of esterified fatty acids. Lipids 28:355-60
Muszbek, L; Laposata, M (1993) Myristoylation of proteins in platelets occurs predominantly through thioester linkages. J Biol Chem 268:8251-5
Muszbek, L; Laposata, M (1993) Covalent modification of proteins by arachidonate and eicosapentaenoate in platelets. J Biol Chem 268:18243-8
Furth, E E; Sprecher, H; Fisher, E A et al. (1992) An in vitro model for essential fatty acid deficiency: HepG2 cells permanently maintained in lipid-free medium. J Lipid Res 33:1719-26

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