Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK047897-07
Application #
6177241
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Program Officer
Haft, Carol R
Project Start
1994-05-01
Project End
2002-04-30
Budget Start
2000-05-01
Budget End
2001-04-30
Support Year
7
Fiscal Year
2000
Total Cost
$215,531
Indirect Cost
Name
Duke University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Yewdell, Jonathan W; Nicchitta, Christopher V (2006) The DRiP hypothesis decennial: support, controversy, refinement and extension. Trends Immunol 27:368-73
Neimark, Ezequiel; Chen, Frank; Li, Xiaoping et al. (2006) c-Fos is a critical mediator of inflammatory-mediated repression of the apical sodium-dependent bile acid transporter. Gastroenterology 131:554-67
Lerner, Rachel S; Nicchitta, Christopher V (2006) mRNA translation is compartmentalized to the endoplasmic reticulum following physiological inhibition of cap-dependent translation. RNA 12:775-89
Stephens, Samuel B; Dodd, Rebecca D; Brewer, Joseph W et al. (2005) Stable ribosome binding to the endoplasmic reticulum enables compartment-specific regulation of mRNA translation. Mol Biol Cell 16:5819-31
Rosser, Meredith F N; Trotta, Brian M; Marshall, Megan R et al. (2004) Adenosine nucleotides and the regulation of GRP94-client protein interactions. Biochemistry 43:8835-45
Baker-LePain, Julie C; Sarzotti, Marcella; Nicchitta, Christopher V (2004) Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo. J Immunol 172:4195-203
Lerner, Rachel S; Seiser, Robert M; Zheng, Tianli et al. (2003) Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes. RNA 9:1123-37
Potter, Matthew D; Nicchitta, Christopher V (2002) Endoplasmic reticulum-bound ribosomes reside in stable association with the translocon following termination of protein synthesis. J Biol Chem 277:23314-20
Seiser, R M; Nicchitta, C V (2000) The fate of membrane-bound ribosomes following the termination of protein synthesis. J Biol Chem 275:33820-7
Potter, M D; Nicchitta, C V (2000) Ribosome-independent regulation of translocon composition and Sec61alpha conformation. J Biol Chem 275:2037-45

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