Perilipins and Adipocyte Lipolysis

Greenberg, Andrew S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK050647-03
• Application #: 6342479
• Study Section: Metabolism Study Section (MET)
• Program Officer: Yanovski, Susan Z
• Project Start: 1999-01-15
• Project End: 2002-12-31
• Budget Start: 2001-01-01
• Budget End: 2001-12-31
• Support Year: 3
• Fiscal Year: 2001
• Total Cost: $252,335

Institution

• Name: Tufts University
• Type: Schools of Medicine
• DUNS #: 604483045
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02111

Publications

Rogers, Nicole H; Perfield 2nd, James W; Strissel, Katherine J et al. (2010) Loss of ovarian function in mice results in abrogated skeletal muscle PPARdelta and FoxO1-mediated gene expression. Biochem Biophys Res Commun 392:1-3

Miyoshi, Hideaki; Souza, Sandra C; Endo, Mikiko et al. (2010) Perilipin overexpression in mice protects against diet-induced obesity. J Lipid Res 51:975-82

Rogers, Nicole H; Perfield 2nd, James W; Strissel, Katherine J et al. (2009) Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology 150:2161-8

Rogers, Nicole H; Witczak, Carol A; Hirshman, Michael F et al. (2009) Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus. Biochem Biophys Res Commun 382:646-50

Danilova, Olga V; Tai, Albert K; Mele, Deanna A et al. (2009) Neurogenin 3-specific dipeptidyl peptidase-2 deficiency causes impaired glucose tolerance, insulin resistance, and visceral obesity. Endocrinology 150:5240-8

Shen, Wen-Jun; Patel, Shailja; Miyoshi, Hideaki et al. (2009) Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res 50:2306-13

D'Eon, Tara M; Rogers, Nicole H; Stancheva, Zlatina S et al. (2008) Estradiol and the estradiol metabolite, 2-hydroxyestradiol, activate AMP-activated protein kinase in C2C12 myotubes. Obesity (Silver Spring) 16:1284-8

Miyoshi, Hideaki; Perfield 2nd, James W; Obin, Martin S et al. (2008) Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes. J Cell Biochem 105:1430-6

Gauthier, Marie-Soleil; Miyoshi, Hideaki; Souza, Sandra C et al. (2008) AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J Biol Chem 283:16514-24

Strissel, Katherine J; Stancheva, Zlatina; Miyoshi, Hideaki et al. (2007) Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes 56:2910-8