Ret Ligand Regulation of Intestinal Motility

Heuckeroth, Robert O.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 1R01DK057038-01
• Application #: 6052680
• Study Section: Special Emphasis Panel (ZRG1-GMA-2 (02))
• Program Officer: Hamilton, Frank A
• Project Start: 2000-04-01
• Project End: 2005-03-31
• Budget Start: 2000-04-01
• Budget End: 2001-03-31
• Support Year: 1
• Fiscal Year: 2000
• Total Cost: $162,618

Institution

• Name: Washington University
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 062761671
• City: Saint Louis
• State: MO
• Country: United States
• Zip Code: 63130

Publications

Lake, Jonathan I; Avetisyan, Marina; Zimmermann, Albert G et al. (2016) Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton. Dev Biol 409:152-165

Fu, Ming; Landreville, Solange; Agapova, Olga A et al. (2013) Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction. J Clin Invest 123:5152-64

Lake, Jonathan I; Tusheva, Olga A; Graham, Brittany L et al. (2013) Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis. J Clin Invest 123:4875-87

Wright-Jin, Elizabeth C; Grider, John R; Duester, Gregg et al. (2013) Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function. Dev Biol 381:28-37

Jain, Sanjay; Knoten, Amanda; Hoshi, Masato et al. (2010) Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice. J Clin Invest 120:778-90

Grider, J R; Heuckeroth, R O; Kuemmerle, J F et al. (2010) Augmentation of the ascending component of the peristaltic reflex and substance P release by glial cell line-derived neurotrophic factor. Neurogastroenterol Motil 22:779-86

Fu, Ming; Sato, Yoshiharu; Lyons-Warren, Ariel et al. (2010) Vitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation. Development 137:631-40

Wang, Hongtao; Hughes, Inna; Planer, William et al. (2010) The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function. J Neurosci 30:1523-38

Zhang, Bin; Chang, Jufang; Fu, Ming et al. (2009) Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. PLoS One 4:e5232

Sato, Yoshiharu; Heuckeroth, Robert O (2008) Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro. Dev Biol 320:185-98