Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK057038-04
Application #
6635227
Study Section
Special Emphasis Panel (ZRG1-GMA-2 (02))
Program Officer
Hamilton, Frank A
Project Start
2000-04-01
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
4
Fiscal Year
2003
Total Cost
$232,019
Indirect Cost

  Institution

Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Lake, Jonathan I; Avetisyan, Marina; Zimmermann, Albert G et al. (2016) Neural crest requires Impdh2 for development of the enteric nervous system, great vessels, and craniofacial skeleton. Dev Biol 409:152-165
Fu, Ming; Landreville, Solange; Agapova, Olga A et al. (2013) Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction. J Clin Invest 123:5152-64
Lake, Jonathan I; Tusheva, Olga A; Graham, Brittany L et al. (2013) Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis. J Clin Invest 123:4875-87
Wright-Jin, Elizabeth C; Grider, John R; Duester, Gregg et al. (2013) Retinaldehyde dehydrogenase enzymes regulate colon enteric nervous system structure and function. Dev Biol 381:28-37
Jain, Sanjay; Knoten, Amanda; Hoshi, Masato et al. (2010) Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice. J Clin Invest 120:778-90
Grider, J R; Heuckeroth, R O; Kuemmerle, J F et al. (2010) Augmentation of the ascending component of the peristaltic reflex and substance P release by glial cell line-derived neurotrophic factor. Neurogastroenterol Motil 22:779-86
Fu, Ming; Sato, Yoshiharu; Lyons-Warren, Ariel et al. (2010) Vitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation. Development 137:631-40
Wang, Hongtao; Hughes, Inna; Planer, William et al. (2010) The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function. J Neurosci 30:1523-38
Zhang, Bin; Chang, Jufang; Fu, Ming et al. (2009) Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. PLoS One 4:e5232
Sato, Yoshiharu; Heuckeroth, Robert O (2008) Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro. Dev Biol 320:185-98

Showing the most recent 10 out of 23 publications