Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK061763-03
Application #
6517999
Study Section
Special Emphasis Panel (ZDK1-GRB-8 (02))
Program Officer
Doo, Edward
Project Start
2000-12-01
Project End
2004-11-30
Budget Start
2001-12-01
Budget End
2002-11-30
Support Year
3
Fiscal Year
2002
Total Cost
$267,075
Indirect Cost
Name
Washington University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Gansner, John M; Gitlin, Jonathan D (2008) Essential role for the alpha 1 chain of type VIII collagen in zebrafish notochord formation. Dev Dyn 237:3715-26
Mendelsohn, Bryce A; Gitlin, Jonathan D (2008) Coordination of development and metabolism in the pre-midblastula transition zebrafish embryo. Dev Dyn 237:1789-98
Thiele, Dennis J; Gitlin, Jonathan D (2008) Assembling the pieces. Nat Chem Biol 4:145-7
Madsen, Erik C; Morcos, Paul A; Mendelsohn, Bryce A et al. (2008) In vivo correction of a Menkes disease model using antisense oligonucleotides. Proc Natl Acad Sci U S A 105:3909-14
Madsen, Erik C; Gitlin, Jonathan D (2008) Zebrafish mutants calamity and catastrophe define critical pathways of gene-nutrient interactions in developmental copper metabolism. PLoS Genet 4:e1000261
Gansner, John M; Mendelsohn, Bryce A; Hultman, Keith A et al. (2007) Essential role of lysyl oxidases in notochord development. Dev Biol 307:202-13
de Bie, Prim; van de Sluis, Bart; Burstein, Ezra et al. (2007) Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B. Gastroenterology 133:1316-26
Madsen, Erik; Gitlin, Jonathan D (2007) Copper and iron disorders of the brain. Annu Rev Neurosci 30:317-37
Madsen, Erik; Gitlin, Jonathan D (2007) Copper deficiency. Curr Opin Gastroenterol 23:187-92
Caruano-Yzermans, Amy L; Bartnikas, Thomas B; Gitlin, Jonathan D (2006) Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase. J Biol Chem 281:13581-7

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