Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004040-08
Application #
2018319
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1986-08-08
Project End
1999-08-31
Budget Start
1996-09-16
Budget End
1997-08-31
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Organized Research Units
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Guity, Partow; McCabe Jr, Michael J; Pitts, David K et al. (2002) Protein kinase C does not mediate the inhibitory action of lead on vitamin D3-dependent production of osteocalcin in osteoblastic bone cells. Toxicol Appl Pharmacol 178:109-16
Pokorski, P L; McCabe Jr, M J; Pounds, J G (1999) Meso-2,3-dimercaptosuccinic acid induces calcium transients in cultured rhesus monkey kidney cells. Toxicology 138:81-91
Pokorski, P L; McCabe Jr, M J; Pounds, J G (1999) Lead inhibits meso-2,3-dimercaptosuccinic acid induced calcium transients in cultured rhesus monkey kidney cells. Toxicology 134:19-26
Pounds, J G; Leggett, R W (1998) The ICRP age-specific biokinetic model for lead: validations, empirical comparisons, and explorations. Environ Health Perspect 106 Suppl 6:1505-11
Long, G J; Pounds, J G; Rosen, J F (1992) Lead intoxication alters basal and parathyroid hormone-regulated cellular calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells. Calcif Tissue Int 50:451-8
Pounds, J G; Long, G J; Rosen, J F (1991) Cellular and molecular toxicity of lead in bone. Environ Health Perspect 91:17-32
Long, G J; Rosen, J F; Pounds, J G (1990) Lead impairs the production of osteocalcin by rat osteosarcoma (ROS 17/2.8) cells. Toxicol Appl Pharmacol 106:270-7
Pounds, J G (1990) The role of cell calcium in current approaches to toxicology. Environ Health Perspect 84:7-15
Long, G J; Rosen, J F; Pounds, J G (1990) Cellular lead toxicity and metabolism in primary and clonal osteoblastic bone cells. Toxicol Appl Pharmacol 102:346-61
Rosen, J F; Pounds, J G (1989) Quantitative interactions between Pb2+ and Ca2+ homeostasis in cultured osteoclastic bone cells. Toxicol Appl Pharmacol 98:530-43

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