Abstract

We propose to investigate the relationship between indoor radon exposure and lung cancer using 350 non-smoking histologically confirmed lung cancer cases and 700 age/sex/smoking history matched controls selected by random-digit-dialing and HCFA payment rosters. The cases will be identified from new cases of lung cancer reported by the Utah and Idaho Cancer Registries. We propose to obtain a lifetime residential history and to measure indoor radon exposure for each case and control. Odds ratios will be calculated relating radon exposure to lung cancer and will be adjusted for confounding by passive smoking, exposure to other hazardous materials such as asbestos, and use of Vitamin A and it precursors.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES004855-03
Application #
3253026
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1988-09-01
Project End
1993-08-31
Budget Start
1990-09-01
Budget End
1991-08-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
University of Utah
Department
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Archer, V E; Lyon, J L (2000) Errors and biases in the diagnosis of cancer of the lung and their influence on risk estimates. Med Hypotheses 54:400-7
Blindauer, K M; Erickson, L; Mcelwee, N et al. (1993) Age and smoking-adjusted lung cancer incidence in a Utah county with a steel mill. Arch Environ Health 48:184-90
Hegmann, K T; Fraser, A M; Keaney, R P et al. (1993) The effect of age at smoking initiation on lung cancer risk. Epidemiology 4:444-8