Mechanisms of Pah Toxicity in Tissue

Jarabak, Joseph W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Research Project (R01)
• Project #: 5R01ES006797-03
• Application #: 2155691
• Study Section: Chemical Pathology Study Section (CPA)
• Project Start: 1994-04-13
• Project End: 1998-03-31
• Budget Start: 1996-04-01
• Budget End: 1998-03-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Chicago
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 225410919
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60637

Publications

Jarabak, R; Harvey, R G; Jarabak, J (1998) Redox cycling of polycyclic aromatic hydrocarbon o-quinones: metal ion-catalyzed oxidation of catechols bypasses inhibition by superoxide dismutase. Chem Biol Interact 115:201-13

Jarabak, R; Harvey, R G; Jarabak, J (1997) Redox cycling of polycyclic aromatic hydrocarbon o-quinones: reversal of superoxide dismutase inhibition by ascorbate. Arch Biochem Biophys 339:92-8

Jarabak, R; Harvey, R G; Jarabak, J (1996) Polycyclic aromatic hydrocarbon quinone-mediated oxidation reduction cycling catalysed by a human placental 17beta-hydroxysteroid dehydrogenase. Arch Biochem Biophys 327:174-80

Jarabak, R; Jarabak, J (1995) Effect of ascorbate on the DT-diaphorase-mediated redox cycling of 2-methyl-1,4-naphthoquinone. Arch Biochem Biophys 318:418-23