Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
1R01ES008043-01
Application #
2157508
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1996-03-01
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Polytechnic Institute and State University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
003137015
City
Blacksburg
State
VA
Country
United States
Zip Code
24061
Fenaux, J B; Gogal Jr, R M; Ahmed, S Ansar (2004) Diethylstilbestrol exposure during fetal development affects thymus: studies in fourteen-month-old mice. J Reprod Immunol 64:75-90
Calemine, Jillian; Zalenka, Julie; Karpuzoglu-Sahin, Ebru et al. (2003) The immune system of geriatric mice is modulated by estrogenic endocrine disruptors (diethylstilbestrol, alpha-zearalanol, and genistein): effects on interferon-gamma. Toxicology 194:115-28
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Karpuzoglu-Sahin, E; Hissong, B D; Ansar Ahmed, S (2001) Interferon-gamma levels are upregulated by 17-beta-estradiol and diethylstilbestrol. J Reprod Immunol 52:113-27
Karpuzoglu-Sahin, E; Zhi-Jun, Y; Lengi, A et al. (2001) Effects of long-term estrogen treatment on IFN-gamma, IL-2 and IL-4 gene expression and protein synthesis in spleen and thymus of normal C57BL/6 mice. Cytokine 14:208-17
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Ahmed, S A; Hissong, B D; Verthelyi, D et al. (1999) Gender and risk of autoimmune diseases: possible role of estrogenic compounds. Environ Health Perspect 107 Suppl 5:681-6
Verthelyi, D I; Ahmed, S A (1998) Estrogen increases the number of plasma cells and enhances their autoantibody production in nonautoimmune C57BL/6 mice. Cell Immunol 189:125-34
Verthelyi, D; Ansar Ahmed, S (1997) Characterization of estrogen-induced autoantibodies to cardiolipin in non-autoimmune mice. J Autoimmun 10:115-25

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