The long term objectives of the proposed research are: (a) to develop a model of the functional organization of the vertebrate visual system based on comparative data from the fields of neuroanatomy, neurophysiology and neuropsychology; (b) to apply the theories and techniques of human psychophysics and scaling, information processing and perception to the animal laboratory to make use of the powerful quantitative and analytical advantages of these methods; (c) to gain a deeper understanding of the mechanisms by which specific cells groups in the vertebrate visual system, especially those that are common to most vertebrates, process visual information; (d) to exploit certain morphological and behavioral advantages that birds offer over non-human mammalian models to investigate structure-function relationships. The ultimate goal of this research is to apply the findings to a better understanding of the human visual system with a particular view towards the amelioration of visual deficits that result from injury to its central processing mechanisms.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY000735-17
Application #
3255526
Study Section
Biopsychology Study Section (BPO)
Project Start
1977-06-01
Project End
1988-05-31
Budget Start
1987-06-01
Budget End
1988-05-31
Support Year
17
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Maryland College Park
Department
Type
Schools of Arts and Sciences
DUNS #
City
College Park
State
MD
Country
United States
Zip Code
20742
Welle, Cristin G; Contreras, Diego (2016) Sensory-driven and spontaneous gamma oscillations engage distinct cortical circuitry. J Neurophysiol 115:1821-35
Denman, Daniel J; Contreras, Diego (2016) On Parallel Streams through the Mouse Dorsal Lateral Geniculate Nucleus. Front Neural Circuits 10:20
Denman, Daniel J; Contreras, Diego (2015) Complex Effects on In Vivo Visual Responses by Specific Projections from Mouse Cortical Layer 6 to Dorsal Lateral Geniculate Nucleus. J Neurosci 35:9265-80
Denman, Daniel J; Contreras, Diego (2014) The structure of pairwise correlation in mouse primary visual cortex reveals functional organization in the absence of an orientation map. Cereb Cortex 24:2707-20
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Chaves, L M; Hodos, W (1998) Color reversal-learning deficits after tectofugal pathway lesions in the pigeon telencephalon. Behav Brain Res 90:1-12
Chaves, L M; Hodos, W (1997) Hyperstriatum ventrale in pigeons: effects of lesions on color-discrimination and color-reversal learning. Vis Neurosci 14:1029-41

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