Abstract

We propose to study normal color vision, and the nature of defects in color which occur in individuals with stationary hereditary color defects ahd those which occur in various retinal and choroidal disease states. We shall use psychophysical techniques to measure the color defects and relate these defects to normal color vision and to the various disease states. We shall use retinal densitometry to study cone visual pigment kinetics in color defective observers and will evaluate the feasibility of studying cone visual pigments kinetics in patients with acquired macular disorders. In addition to empirical studies, we develop models of normal and abnormal color vision. Our theoretical approach is based in the question: To what extent can established biological or physical phenomena explain the data of color vision: This approach is one which allows us to examine the plausibility of various hypotheses which are not subject to direct experimental evaluation.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY000901-13
Application #
3255592
Study Section
Biopsychology Study Section (BPO)
Project Start
1977-04-01
Project End
1987-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
13
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
University of Chicago
Department
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637

  Publications

Pokorny, Joel; Smith, Vivianne C; Xu, Jun (2012) Quantal and non-quantal color matches: failure of Grassmann's laws at short wavelengths. J Opt Soc Am A Opt Image Sci Vis 29:A324-36
Cao, Dingcai; Pokorny, Joel (2010) Rod and cone contrast gains derived from reaction time distribution modeling. J Vis 10:11.1-15
Lee, Barry B; Smith, Vivianne C; Pokorny, Joel et al. (2008) Chromatic adaptation in red-green cone-opponent retinal ganglion cells of the macaque. Vision Res 48:2625-32
Smith, Vivianne C; Pokorny, Joel; Lee, Barry B et al. (2008) Sequential processing in vision: The interaction of sensitivity regulation and temporal dynamics. Vision Res 48:2649-56
Pokorny, Joel; Lutze, Margaret; Cao, Dingcai et al. (2008) The color of night: surface color categorization by color defective observers under dim illuminations. Vis Neurosci 25:475-80
Cao, Dingcai; Pokorny, Joel; Smith, Vivianne C et al. (2008) Rod contributions to color perception: linear with rod contrast. Vision Res 48:2586-92
Cao, Dingcai; Zele, Andrew J; Smith, Vivianne C et al. (2008) S-cone discrimination for stimuli with spatial and temporal chromatic contrast. Vis Neurosci 25:349-54
Cao, Dingcai; Zele, Andrew J; Pokorny, Joel (2008) Chromatic discrimination in the presence of incremental and decremental rod pedestals. Vis Neurosci 25:399-404
Zele, Andrew J; Cao, Dingcai; Pokorny, Joel (2008) Rod-cone interactions and the temporal impulse response of the cone pathway. Vision Res 48:2593-8
Gamlin, Paul D R; McDougal, David H; Pokorny, Joel et al. (2007) Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Vision Res 47:946-54

Showing the most recent 10 out of 73 publications