Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY002227-17
Application #
2158384
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1978-03-01
Project End
1997-02-28
Budget Start
1994-03-01
Budget End
1997-02-28
Support Year
17
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Florida
Department
Pharmacology
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Maren, T H (2000) Carbonic anhydrase inhibition in ophthalmology: aqueous humor secretion and the development of sulfonamide inhibitors. EXS :425-35
Conroy, C W; Maren, T H (1999) Corneal sequestration and delivery to ciliary process of six topically applied sulfonamides. J Ocul Pharmacol Ther 15:179-87
Wistrand, P J; Carter, N D; Conroy, C W et al. (1999) Carbonic anhydrase IV activity is localized on the exterior surface of human erythrocytes. Acta Physiol Scand 165:211-8
Conroy, C W; Maren, T H (1998) The ocular distribution of methazolamide after corneal and scleral administration: the effect of ionization state. J Ocul Pharmacol Ther 14:565-73
Maren, T H; Godman, D R; Pancorbo, B M et al. (1997) Timolol decreases aqueous humor flow but not Na+ movement from plasma to aqueous. Invest Ophthalmol Vis Sci 38:1274-7
Maren, T H; Conroy, C W; Wynns, G C et al. (1997) Ocular absorption, blood levels, and excretion of dorzolamide, a topically active carbonic anhydrase inhibitor. J Ocul Pharmacol Ther 13:23-30
Maren, T H; Conroy, C W; Wynns, G C et al. (1997) Renal and cerebrospinal fluid formation pharmacology of a high molecular weight carbonic anhydrase inhibitor. J Pharmacol Exp Ther 280:98-104
Conroy, C W (1997) Sulfonamides do not reach the retina in therapeutic amounts after topical application to the cornea. J Ocul Pharmacol Ther 13:465-72
Maren, T H (1997) Sulfonamides and secretion of aqueous humor. J Exp Zool 279:490-7
Supuran, C T; Conroy, C W; Maren, T H (1997) Is cyanate a carbonic anhydrase substrate? Proteins 27:272-8

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