Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
3R01EY003754-06S1
Application #
3258194
Study Section
Biophysics and Biophysical Chemistry B Study Section (BBCB)
Project Start
1981-05-01
Project End
1987-04-30
Budget Start
1986-05-01
Budget End
1987-04-30
Support Year
6
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Virginia
Department
Type
Schools of Arts and Sciences
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Salamon, Z; Wang, Y; Soulages, J L et al. (1996) Surface plasmon resonance spectroscopy studies of membrane proteins: transducin binding and activation by rhodopsin monitored in thin membrane films. Biophys J 71:283-94
Brown, M F (1994) Modulation of rhodopsin function by properties of the membrane bilayer. Chem Phys Lipids 73:159-80
Salamon, Z; Wang, Y; Brown, M F et al. (1994) Conformational changes in rhodopsin probed by surface plasmon resonance spectroscopy. Biochemistry 33:13706-11
Thurmond, R L; Lindblom, G; Brown, M F (1993) Curvature, order, and dynamics of lipid hexagonal phases studied by deuterium NMR spectroscopy. Biochemistry 32:5394-410
Gibson, N J; Brown, M F (1993) Lipid headgroup and acyl chain composition modulate the MI-MII equilibrium of rhodopsin in recombinant membranes. Biochemistry 32:2438-54
Gibson, N J; Brown, M F (1991) Membrane lipid influences on the energetics of the metarhodopsin I and metarhodopsin II conformational states of rhodopsin probed by flash photolysis. Photochem Photobiol 54:985-92
Gibson, N J; Brown, M F (1991) Role of phosphatidylserine in the MI-MII equilibrium of rhodopsin. Biochem Biophys Res Commun 176:915-21
Barry, J A; Trouard, T P; Salmon, A et al. (1991) Low-temperature 2H NMR spectroscopy of phospholipid bilayers containing docosahexaenoyl (22:6 omega 3) chains. Biochemistry 30:8386-94
Thurmond, R L; Dodd, S W; Brown, M F (1991) Molecular areas of phospholipids as determined by 2H NMR spectroscopy. Comparison of phosphatidylethanolamines and phosphatidylcholines. Biophys J 59:108-13
Rajamoorthi, K; Brown, M F (1991) Bilayers of arachidonic acid containing phospholipids studied by 2H and 31P NMR spectroscopy. Biochemistry 30:4204-12

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