Abstract

Messenger activity has been detected by in vitro translation and specific immunoprecipitation, for the capsid polypeptide (SCV-Pl) and the presumed intracellular precursor (M-Pl, 32k. daltons) of the exocellular toxin (tox-l, 12 k. daltons) produced by killer strains of the yeast, Saccharomyces cerevisiae. Messenger will be quantitated throughout the yeast cell cycle and will be characterized for 5' caps and 3' polyadenylation. Maturation of M-Pl will be studied using membrane preparations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM020755-08
Application #
3270151
Study Section
Molecular Biology Study Section (MBY)
Project Start
1978-09-01
Project End
1986-03-31
Budget Start
1984-12-01
Budget End
1986-03-31
Support Year
8
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of Massachusetts Medical School Worcester
Department
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code