Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM032567-11
Application #
2176651
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1988-08-01
Project End
1998-01-31
Budget Start
1995-12-01
Budget End
1998-01-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Temple University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Swanljung-Collins, H; Collins, J H (1994) Brush border myosin I has a calmodulin/phosphatidylserine switch and tail actin-binding. Adv Exp Med Biol 358:205-13
Swanljung-Collins, H; Collins, J H (1992) Phosphorylation of brush border myosin I by protein kinase C is regulated by Ca(2+)-stimulated binding of myosin I to phosphatidylserine concerted with calmodulin dissociation. J Biol Chem 267:3445-54
Swanljung-Collins, H; Collins, J H (1991) Rapid, high-yield purification of intestinal brush border myosin I. Methods Enzymol 196:3-11
Swanljung-Collins, H; Collins, J H (1991) Ca2+ stimulates the Mg2(+)-ATPase activity of brush border myosin I with three or four calmodulin light chains but inhibits with less than two bound. J Biol Chem 266:1312-9
Borysenko, C; Rieker, J P; Swanljung-Collins, H et al. (1988) Phosphorylation of brush border myosin at threonine on its 20 kDa light chains by a calmodulin-independent kinase activates its ATPase. FEBS Lett 235:149-52
Rieker, J P; Swanljung-Collins, H; Collins, J H (1987) Purification and characterization of a calmodulin-dependent myosin heavy chain kinase from intestinal brush border. J Biol Chem 262:15262-8
Swanljung-Collins, H; Montibeller, J; Collins, J H (1987) Purification and characterization of the 110-kDa actin- and calmodulin-binding protein from intestinal brush border: a myosin-like ATPase. Methods Enzymol 139:137-48
Rieker, J P; Collins, J H (1987) Phosphorylation of brush border myosin by brush border calmodulin-dependent myosin heavy and light chain kinases. FEBS Lett 223:262-6
Rieker, J P; Swanljung-Collins, H; Montibeller, J et al. (1987) Isolation and characterization of calmodulin-dependent myosin heavy chain kinase from intestinal brush border. Methods Enzymol 139:105-14
Rieker, J P; Swanljung-Collins, H; Montibeller, J et al. (1987) Brush border myosin heavy chain phosphorylation is regulated by calcium and calmodulin. FEBS Lett 212:154-8