Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM039372-06
Application #
2179791
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1988-04-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Bar-Ilan University
Department
Type
DUNS #
City
Ramat Gan
State
Country
Israel
Zip Code
52900
Ratner, V; Amir, D; Kahana, E et al. (2005) Fast collapse but slow formation of secondary structure elements in the refolding transition of E. coli adenylate kinase. J Mol Biol 352:683-99
Ratner, V; Kahana, E; Eichler, M et al. (2002) A general strategy for site-specific double labeling of globular proteins for kinetic FRET studies. Bioconjug Chem 13:1163-70
Ratner, V; Kahana, E; Haas, E (2002) The natively helical chain segment 169-188 of Escherichia coli adenylate kinase is formed in the latest phase of the refolding transition. J Mol Biol 320:1135-45
Navon, Ami; Ittah, Varda; Scheraga, Harold A et al. (2002) Formation of the hydrophobic core of ribonuclease A through sequential coordinated conformational transitions. Biochemistry 41:14225-31
Navon, A; Ittah, V; Laity, J H et al. (2001) Local and long-range interactions in the thermal unfolding transition of bovine pancreatic ribonuclease A. Biochemistry 40:93-104
Navon, A; Ittah, V; Landsman, P et al. (2001) Distributions of intramolecular distances in the reduced and denatured states of bovine pancreatic ribonuclease A. Folding initiation structures in the C-terminal portions of the reduced protein. Biochemistry 40:105-18
Sinev, M; Landsmann, P; Sineva, E et al. (2000) Design consideration and probes for fluorescence resonance energy transfer studies. Bioconjug Chem 11:352-62
Shapiro, Y E; Sinev, M A; Sineva, E V et al. (2000) Backbone dynamics of escherichia coli adenylate kinase at the extreme stages of the catalytic cycle studied by (15)N NMR relaxation. Biochemistry 39:6634-44
Ratner, V; Sinev, M; Haas, E (2000) Determination of intramolecular distance distribution during protein folding on the millisecond timescale. J Mol Biol 299:1363-71
Ittah, V; Haas, E (1995) Nonlocal interactions stabilize long range loops in the initial folding intermediates of reduced bovine pancreatic trypsin inhibitor. Biochemistry 34:4493-506

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