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Lee, Darren; Ohn, Takbum; Chiang, Yueh-Chin et al. (2010) PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure. J Mol Biol 399:562-75
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Cui, Yajun; Ramnarain, Deepti B; Chiang, Yueh-Chin et al. (2008) Genome wide expression analysis of the CCR4-NOT complex indicates that it consists of three modules with the NOT module controlling SAGA-responsive genes. Mol Genet Genomics 279:323-37
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Ohn, Takbum; Chiang, Yueh-Chin; Lee, Darren J et al. (2007) CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4. Nucleic Acids Res 35:3002-15
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Traven, Ana; Hammet, Andrew; Tenis, Nora et al. (2005) Ccr4-not complex mRNA deadenylase activity contributes to DNA damage responses in Saccharomyces cerevisiae. Genetics 169:65-75
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Clark, Lisa B; Viswanathan, Palaniswamy; Quigley, Gloria et al. (2004) Systematic mutagenesis of the leucine-rich repeat (LRR) domain of CCR4 reveals specific sites for binding to CAF1 and a separate critical role for the LRR in CCR4 deadenylase activity. J Biol Chem 279:13616-23
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Viswanathan, Palaniswamy; Ohn, Takbum; Chiang, Yueh-Chin et al. (2004) Mouse CAF1 can function as a processive deadenylase/3'-5'-exonuclease in vitro but in yeast the deadenylase function of CAF1 is not required for mRNA poly(A) removal. J Biol Chem 279:23988-95
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Chen, Junji; Chiang, Yueh-Chin; Denis, Clyde L (2002) CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase. EMBO J 21:1414-26
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Tucker, M; Valencia-Sanchez, M A; Staples, R R et al. (2001) The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell 104:377-86
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Chen, J; Rappsilber, J; Chiang, Y C et al. (2001) Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. J Mol Biol 314:683-94
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Badarinarayana, V; Chiang, Y C; Denis, C L (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155:1045-54
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Showing the most recent 10 out of 25 publications
