Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM041967-07
Application #
2181162
Study Section
Molecular Biology Study Section (MBY)
Project Start
1990-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Weill Medical College of Cornell University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
201373169
City
New York
State
NY
Country
United States
Zip Code
10065

  Publications

Prescott, J C; Liu, L; Falck-Pedersen, E (1997) Sequence-mediated regulation of adenovirus gene expression by repression of mRNA accumulation. Mol Cell Biol 17:2207-16
Gershengorn, M C; Heinflink, M; Nussenzveig, D R et al. (1994) Thyrotropin-releasing hormone (TRH) receptor number determines the size of the TRH-responsive phosphoinositide pool. Demonstration using controlled expression of TRH receptors by adenovirus mediated gene transfer. J Biol Chem 269:6779-83
Kass-Eisler, A; Falck-Pedersen, E; Elfenbein, D H et al. (1994) The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer. Gene Ther 1:395-402
Falck-Pedersen, E; Heinflink, M; Alvira, M et al. (1994) Expression of thyrotropin-releasing hormone receptors by adenovirus-mediated gene transfer reveals that thyrotropin-releasing hormone desensitization is cell specific. Mol Pharmacol 45:684-9
Kass-Eisler, A; Falck-Pedersen, E; Alvira, M et al. (1993) Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo. Proc Natl Acad Sci U S A 90:11498-502
Tantravahi, J; Alvira, M; Falck-Pedersen, E (1993) Characterization of the mouse beta maj globin transcription termination region: a spacing sequence is required between the poly(A) signal sequence and multiple downstream termination elements. Mol Cell Biol 13:578-87
Edwalds-Gilbert, G; Prescott, J; Falck-Pedersen, E (1993) 3' RNA processing efficiency plays a primary role in generating termination-competent RNA polymerase II elongation complexes. Mol Cell Biol 13:3472-80
Prescott, J C; Falck-Pedersen, E (1992) Varied poly(A) site efficiency in the adenovirus major late transcription unit. J Biol Chem 267:8175-81
DeZazzo, J D; Falck-Pedersen, E; Imperiale, M J (1991) Sequences regulating temporal poly(A) site switching in the adenovirus major late transcription unit. Mol Cell Biol 11:5977-84