Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM043751-06
Application #
2182155
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1991-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Physiology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Lambert, A; Ekambaram, M; Robinson, N et al. (2000) Transglutaminase reactivity of human involucrin. Skin Pharmacol Appl Skin Physiol 13:17-30
Agarwal, C; Efimova, T; Welter, J F et al. (1999) CCAAT/enhancer-binding proteins. A role in regulation of human involucrin promoter response to phorbol ester. J Biol Chem 274:6190-4
LaCelle, P T; Lambert, A; Ekambaram, M C et al. (1998) In vitro cross-linking of recombinant human involucrin. Skin Pharmacol Appl Skin Physiol 11:214-26
Robinson, N A; Eckert, R L (1998) Identification of transglutaminase-reactive residues in S100A11. J Biol Chem 273:2721-8
Eckert, R L; Crish, J F; Robinson, N A (1997) The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Physiol Rev 77:397-424
Eckert, R L; Crish, J F; Banks, E B et al. (1997) The epidermis: genes on - genes off. J Invest Dermatol 109:501-9
Robinson, N A; Lapic, S; Welter, J F et al. (1997) S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes. J Biol Chem 272:12035-46
Robinson, N A; LaCelle, P T; Eckert, R L (1996) Involucrin is a covalently crosslinked constituent of highly purified epidermal corneocytes: evidence for a common pattern of involucrin crosslinking in vivo and in vitro. J Invest Dermatol 107:101-7
Eckert, R L; Welter, J F (1996) Transcription factor regulation of epidermal keratinocyte gene expression. Mol Biol Rep 23:59-70
Yaffe, M B; Murthy, S; Eckert, R L (1993) Evidence that involucrin is a covalently linked constituent of highly purified cultured keratinocyte cornified envelopes. J Invest Dermatol 100:3-9

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