Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM044286-12
Application #
6645401
Study Section
Mammalian Genetics Study Section (MGN)
Program Officer
Carter, Anthony D
Project Start
1991-01-01
Project End
2005-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
12
Fiscal Year
2003
Total Cost
$298,904
Indirect Cost

  Institution

Name
University of Florida
Department
Biochemistry
Type
Schools of Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Rodriguez-Jato, Sara; Nicholls, Robert D; Driscoll, Daniel J et al. (2005) Characterization of cis- and trans-acting elements in the imprinted human SNURF-SNRPN locus. Nucleic Acids Res 33:4740-53
Kang, Sung-Hae Lee; Kiefer, Christine Mione; Yang, Thomas P (2003) Role of the promoter in maintaining transcriptionally active chromatin structure and DNA methylation patterns in vivo. Mol Cell Biol 23:4150-61
Brooks, W H; Satoh, M; Hong, B et al. (2002) Autoantibodies from an SLE patient immunostain the Barr body. Cytogenet Genome Res 97:28-31
Chen, C; Yang, M C; Yang, T P (2001) Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites. J Biol Chem 276:320-8
Hong, B; Reeves, P; Panning, B et al. (2001) Identification of an autoimmune serum containing antibodies against the Barr body. Proc Natl Acad Sci U S A 98:8703-8
Chen, C; Yang, T P (2001) Nucleosomes are translationally positioned on the active allele and rotationally positioned on the inactive allele of the HPRT promoter. Mol Cell Biol 21:7682-95
Litt, M D; Hansen, R S; Hornstra, I K et al. (1997) 5-Azadeoxycytidine-induced chromatin remodeling of the inactive X-linked HPRT gene promoter occurs prior to transcription factor binding and gene reactivation. J Biol Chem 272:14921-6
Litt, M D; Hornstra, I K; Yang, T P (1996) In vivo footprinting and high-resolution methylation analysis of the mouse hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes. Mol Cell Biol 16:6190-9
Rincon-Limas, D E; Amaya-Manzanares, F; Nino-Rosales, M L et al. (1995) Ubiquitous and neuronal DNA-binding proteins interact with a negative regulatory element of the human hypoxanthine phosphoribosyltransferase gene. Mol Cell Biol 15:6561-71
Hornstra, I K; Yang, T P (1994) High-resolution methylation analysis of the human hypoxanthine phosphoribosyltransferase gene 5' region on the active and inactive X chromosomes: correlation with binding sites for transcription factors. Mol Cell Biol 14:1419-30

Showing the most recent 10 out of 13 publications