Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM046931-05
Application #
2184413
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1992-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical Biology Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Richieri, G V; Ogata, R T; Zimmerman, A W et al. (2000) Fatty acid binding proteins from different tissues show distinct patterns of fatty acid interactions. Biochemistry 39:7197-204
Richieri, G V; Low, P J; Ogata, R T et al. (1999) Binding kinetics of engineered mutants provide insight about the pathway for entering and exiting the intestinal fatty acid binding protein. Biochemistry 38:5888-95
Richieri, G V; Ogata, R T; Kleinfeld, A M (1999) Fatty acid interactions with native and mutant fatty acid binding proteins. Mol Cell Biochem 192:77-85
Richieri, G V; Ogata, R T; Kleinfeld, A M (1999) The measurement of free fatty acid concentration with the fluorescent probe ADIFAB: a practical guide for the use of the ADIFAB probe. Mol Cell Biochem 192:87-94
Richieri, G V; Low, P J; Ogata, R T et al. (1998) Thermodynamics of fatty acid binding to engineered mutants of the adipocyte and intestinal fatty acid-binding proteins. J Biol Chem 273:7397-405
Richieri, G V; Low, P J; Ogata, R T et al. (1997) Mutants of rat intestinal fatty acid-binding protein illustrate the critical role played by enthalpy-entropy compensation in ligand binding. J Biol Chem 272:16737-40
Richieri, G V; Ogata, R T; Kleinfeld, A M (1996) Thermodynamic and kinetic properties of fatty acid interactions with rat liver fatty acid-binding protein. J Biol Chem 271:31068-74
Richieri, G V; Ogata, R T; Kleinfeld, A M (1996) Kinetics of fatty acid interactions with fatty acid binding proteins from adipocyte, heart, and intestine. J Biol Chem 271:11291-300
Richieri, G V; Ogata, R T; Kleinfeld, A M (1995) Thermodynamics of fatty acid binding to fatty acid-binding proteins and fatty acid partition between water and membranes measured using the fluorescent probe ADIFAB. J Biol Chem 270:15076-84
Richieri, G V; Ogata, R T; Kleinfeld, A M (1994) Equilibrium constants for the binding of fatty acids with fatty acid-binding proteins from adipocyte, intestine, heart, and liver measured with the fluorescent probe ADIFAB. J Biol Chem 269:23918-30