Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM052311-01A1
Application #
2191282
Study Section
Molecular Biology Study Section (MBY)
Project Start
1996-02-09
Project End
2000-01-31
Budget Start
1996-02-09
Budget End
1997-01-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
University Park
State
PA
Country
United States
Zip Code
16802
Ercan, Sevinc; Reese, Joseph C; Workman, Jerry L et al. (2005) Yeast recombination enhancer is stimulated by transcription activation. Mol Cell Biol 25:7976-87
Simpson, Robert T; Ducker, Charles E; Diller, John D et al. (2004) Purification of native, defined chromatin segments. Methods Enzymol 375:158-70
Ercan, Sevinc; Simpson, Robert T (2004) Global chromatin structure of 45,000 base pairs of chromosome III in a- and alpha-cell yeast and during mating-type switching. Mol Cell Biol 24:10026-35
Ducker, C E; Simpson, R T (2000) The organized chromatin domain of the repressed yeast a cell-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome. EMBO J 19:400-9
Gavin, I M; Kladde, M P; Simpson, R T (2000) Tup1p represses Mcm1p transcriptional activation and chromatin remodeling of an a-cell-specific gene. EMBO J 19:5875-83
Ravindra, A; Weiss, K; Simpson, R T (1999) High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa. Mol Cell Biol 19:7944-50
Weiss, K; Simpson, R T (1998) High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLalpha. Mol Cell Biol 18:5392-403
Simpson, R T (1998) Chromatin structure and analysis of mechanisms of activators and repressors. Methods 15:283-94
Wu, C; Weiss, K; Yang, C et al. (1998) Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching. Genes Dev 12:1726-37
Gavin, I M; Simpson, R T (1997) Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure. EMBO J 16:6263-71

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