Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM058832-01A1
Application #
2903212
Study Section
Medicinal Chemistry Study Section (MCHA)
Project Start
1999-08-01
Project End
2004-07-31
Budget Start
1999-08-01
Budget End
2000-07-31
Support Year
1
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Pennsylvania State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
City
University Park
State
PA
Country
United States
Zip Code
16802
Li, Shengkun; Huang, Kexuan; Zhang, Xumu (2014) Enantioselective hydrogenation of ?,?-disubstituted nitroalkenes. Chem Commun (Camb) 50:8878-81
Chang, Mingxin; Huang, Yuhua; Liu, Shaodong et al. (2014) Asymmetric hydrogenation of pyridinium salts with an iridium phosphole catalyst. Angew Chem Int Ed Engl 53:12761-4
Li, Shengkun; Huang, Kexuan; Zhang, Jiwen et al. (2013) Rhodium-catalyzed highly regioselective hydroaminomethylation of styrenes with tetraphosphorus ligands. Org Lett 15:3078-81
Liu, Tang-Lin; Li, Wei; Geng, Huiling et al. (2013) Catalytic enantioselective desymmetrization of meso cyclic anhydrides via iridium-catalyzed hydrogenation. Org Lett 15:1740-3
Li, Shengkun; Huang, Kexuan; Zhang, Jiwen et al. (2013) Rh-catalyzed highly enantioselective hydrogenation of nitroalkenes under basic conditions. Chemistry 19:10840-4
Huang, Kexuan; Li, Shengkun; Chang, Mingxin et al. (2013) Rhodium-catalyzed enantioselective hydrogenation of oxime acetates. Org Lett 15:484-7
Li, Shengkun; Huang, Kexuan; Zhang, Jiwen et al. (2013) Cascade synthesis of fenpiprane and related pharmaceuticals via rhodium-catalyzed hydroaminomethylation. Org Lett 15:1036-9
Li, Shengkun; Huang, Kexuan; Cao, Bonan et al. (2012) Highly enantioselective hydrogenation of ýý,ýý-disubstituted nitroalkenes. Angew Chem Int Ed Engl 51:8573-6
Chang, Mingxin; Li, Wei; Zhang, Xumu (2011) A highly efficient and enantioselective access to tetrahydroisoquinoline alkaloids: asymmetric hydrogenation with an iridium catalyst. Angew Chem Int Ed Engl 50:10679-81
Geng, Huiling; Huang, Kexuan; Sun, Tian et al. (2011) Enantioselective synthesis of optically pure ýý-amino ketones and ýý-aryl amines by Rh-catalyzed asymmetric hydrogenation. J Org Chem 76:332-4

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