Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM066839-02
Application #
6693402
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Program Officer
Somers, Scott D
Project Start
2003-01-01
Project End
2004-07-31
Budget Start
2004-01-01
Budget End
2004-07-31
Support Year
2
Fiscal Year
2004
Total Cost
$105,217
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Sun, Lei; Pham, Tiffany T; Cornell, Timothy T et al. (2017) Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge. J Immunol 198:404-416
Sun, L; Cornell, T T; LeVine, A et al. (2013) Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation. Clin Exp Immunol 172:263-79
Cornell, Timothy T; Fleszar, Andrew; McHugh, Walker et al. (2012) Mitogen-activated protein kinase phosphatase 2, MKP-2, regulates early inflammation in acute lung injury. Am J Physiol Lung Cell Mol Physiol 303:L251-8
Sun, Lei; Louie, Marisa C; Vannella, Kevin M et al. (2011) New concepts of IL-10-induced lung fibrosis: fibrocyte recruitment and M2 activation in a CCL2/CCR2 axis. Am J Physiol Lung Cell Mol Physiol 300:L341-53
El-Wiher, Nidal; Cornell, Timothy T; Kissoon, Nranjany et al. (2011) Management and Treatment Guidelines for Sepsis in Pediatric Patients. Open Inflamm J 4:101-109
Cornell, Timothy T; Rodenhouse, Paul; Cai, Qing et al. (2010) Mitogen-activated protein kinase phosphatase 2 regulates the inflammatory response in sepsis. Infect Immun 78:2868-76
Wynn, James; Cornell, Timothy T; Wong, Hector R et al. (2010) The host response to sepsis and developmental impact. Pediatrics 125:1031-41
Cornell, Timothy T; Wynn, James; Shanley, Thomas P et al. (2010) Mechanisms and regulation of the gene-expression response to sepsis. Pediatrics 125:1248-58
Liu, Yusen; Shanley, Thomas P (2009) MAP Kinase Phosphatase-1 and Septic Shock. J Organ Dysfunct 5:68-78
Cornell, Timothy T; Hinkovska-Galcheva, Vania; Sun, Lei et al. (2009) Ceramide-dependent PP2A regulation of TNFalpha-induced IL-8 production in respiratory epithelial cells. Am J Physiol Lung Cell Mol Physiol 296:L849-56

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