Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM071552-01S1
Application #
6950650
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Program Officer
Lewis, Catherine D
Project Start
2004-07-01
Project End
2008-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
1
Fiscal Year
2004
Total Cost
$76,000
Indirect Cost
Name
University of California Berkeley
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Tafoya, Sara; Liu, Shixin; Castillo, Juan P et al. (2018) Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase. Proc Natl Acad Sci U S A 115:7961-7966
Righini, Maurizio; Lee, Antony; CaƱari-Chumpitaz, Cristhian et al. (2018) Full molecular trajectories of RNA polymerase at single base-pair resolution. Proc Natl Acad Sci U S A 115:1286-1291
Gabizon, Ronen; Lee, Antony; Vahedian-Movahed, Hanif et al. (2018) Pause sequences facilitate entry into long-lived paused states by reducing RNA polymerase transcription rates. Nat Commun 9:2930
Lee, Antony; Tsekouras, Konstantinos; Calderon, Christopher et al. (2017) Unraveling the Thousand Word Picture: An Introduction to Super-Resolution Data Analysis. Chem Rev 117:7276-7330
Liu, Shixin; Tafoya, Sara; Bustamante, Carlos (2017) Deciphering the Molecular Mechanism of the Bacteriophage ?29 DNA Packaging Motor. Methods Mol Biol 1486:343-355
Rodriguez-Aliaga, Piere; Ramirez, Luis; Kim, Frank et al. (2016) Substrate-translocating loops regulate mechanochemical coupling and power production in AAA+ protease ClpXP. Nat Struct Mol Biol 23:974-981
Jardine, Paul J (2016) Packaging Models versus Modeling Packaging. Biophys J 110:287-288
Liu, Ninning; Chistol, Gheorghe; Bustamante, Carlos (2015) Two-subunit DNA escort mechanism and inactive subunit bypass in an ultra-fast ring ATPase. Elife 4:
Liu, Shixin; Chistol, Gheorghe; Bustamante, Carlos (2014) Mechanical operation and intersubunit coordination of ring-shaped molecular motors: insights from single-molecule studies. Biophys J 106:1844-58
Liu, Shixin; Chistol, Gheorghe; Hetherington, Craig L et al. (2014) A viral packaging motor varies its DNA rotation and step size to preserve subunit coordination as the capsid fills. Cell 157:702-713

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