Cellular Messengers at Fertilization in Mammalian Eggs

Kline, Douglas W.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Research Project (R01)
• Project #: 5R01HD026032-02
• Application #: 3327387
• Study Section: Reproductive Biology Study Section (REB)
• Project Start: 1988-12-01
• Project End: 1990-06-30
• Budget Start: 1989-12-01
• Budget End: 1990-06-30
• Support Year: 2
• Fiscal Year: 1990

Institution

• Name: Ponce School of Medicine
• Type: Schools of Medicine
• City: Ponce
• State: PR
• Country: United States
• Zip Code: 00732

Publications

Kline, D; Zagray, J A (1995) Absence of an intracellular pH change following fertilisation of the mouse egg. Zygote 3:305-11

Kline, J T; Kline, D (1994) Regulation of intracellular calcium in the mouse egg: evidence for inositol trisphosphate-induced calcium release, but not calcium-induced calcium release. Biol Reprod 50:193-203

Kline, D; Stewart-Savage, J (1994) The timing of cortical granule fusion, content dispersal, and endocytosis during fertilization of the hamster egg: an electrophysiological and histochemical study. Dev Biol 162:277-87

Kline, D; Kline, J T (1992) Thapsigargin activates a calcium influx pathway in the unfertilized mouse egg and suppresses repetitive calcium transients in the fertilized egg. J Biol Chem 267:17624-30

Kline, D; Kline, J T (1992) Repetitive calcium transients and the role of calcium in exocytosis and cell cycle activation in the mouse egg. Dev Biol 149:80-9

Kline, D; Kopf, G S; Muncy, L F et al. (1991) Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog, Xenopus laevis. Dev Biol 143:218-29