Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD026485-04A3
Application #
2199977
Study Section
Reproductive Biology Study Section (REB)
Project Start
1991-05-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Pediatrics
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Tsuruta, J K; Eddy, E M; O'Brien, D A (2000) Insulin-like growth factor-II/cation-independent mannose 6-phosphate receptor mediates paracrine interactions during spermatogonial development. Biol Reprod 63:1006-13
Franklin, D S; Godfrey, V L; O'Brien, D A et al. (2000) Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity. Mol Cell Biol 20:6147-58
Pace, A J; Lee, E; Athirakul, K et al. (2000) Failure of spermatogenesis in mouse lines deficient in the Na(+)-K(+)-2Cl(-) cotransporter. J Clin Invest 105:441-50
McCarrey, J R; O'Brien, D A; Skinner, M K (1999) Construction and preliminary characterization of a series of mouse and rat testis cDNA libraries. J Androl 20:635-9
Eddy, E M; O'Brien, D A (1998) Gene expression during mammalian meiosis. Curr Top Dev Biol 37:141-200
Joseph, D R; O'Brien, D A; Sullivan, P M et al. (1997) Overexpression of androgen-binding protein/sex hormone-binding globulin in male transgenic mice: tissue distribution and phenotypic disorders. Biol Reprod 56:21-32
O'Brien, D A; Welch, J E; Goulding, E H et al. (1996) Boar proacrosin expressed in spermatids of transgenic mice does not reach the acrosome and disrupts spermatogenesis. Mol Reprod Dev 43:236-47
Raburn, D J; Hamil, K G; Tsuruta, J K et al. (1995) Stage-specific expression of B cell translocation gene 1 in rat testis. Endocrinology 136:5769-77
Fulcher, K D; Welch, J E; Klapper, D G et al. (1995) Identification of a unique mu-class glutathione S-transferase in mouse spermatogenic cells. Mol Reprod Dev 42:415-24
Welch, J E; Brown, P R; O'Brien, D A et al. (1995) Genomic organization of a mouse glyceraldehyde 3-phosphate dehydrogenase gene (Gapd-s) expressed in post-meiotic spermatogenic cells. Dev Genet 16:179-89

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