Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL043318-03
Application #
3361927
Study Section
Special Emphasis Panel (SRC (CD))
Project Start
1989-07-01
Project End
1994-04-30
Budget Start
1991-05-10
Budget End
1992-04-30
Support Year
3
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Russell, M E; Hancock, W W; Wallace, A F et al. (1995) Modulation of inflammatory activation pathways in the Lewis-to-F-344 rat chronic cardiac rejection model. Transplant Proc 27:2100-4
Shin, Y T; Adams, D H; Wyner, L R et al. (1995) Intrathymic tolerance in the Lewis-to-F344 chronic cardiac allograft rejection model. Transplantation 59:1647-53
Russell, M E; Wallace, A F; Wyner, L R et al. (1995) Upregulation and modulation of inducible nitric oxide synthase in rat cardiac allografts with chronic rejection and transplant arteriosclerosis. Circulation 92:457-64
Russell, M E; Wallace, A F; Hancock, W W et al. (1995) Upregulation of cytokines associated with macrophage activation in the Lewis-to-F344 rat transplantation model of chronic cardiac rejection. Transplantation 59:572-8
Shin, Y T; Adams, D H; Wyner, L R et al. (1995) Intrathymic injection of donor splenocytes plus systemic antilymphocyte serum or antilymphocyte serum alone prolongs cardiac allograft survival and inhibits graft arteriosclerosis in the Lewis-to-F344 chronic rejection model. Transplant Proc 27:2112-4
Utans, U; Liang, P; Wyner, L R et al. (1994) Chronic cardiac rejection: identification of five upregulated genes in transplanted hearts by differential mRNA display. Proc Natl Acad Sci U S A 91:6463-7
Russell, M E; Utans, U; Wallace, A F et al. (1994) Identification and upregulation of galactose/N-acetylgalactosamine macrophage lectin in rat cardiac allografts with arteriosclerosis. J Clin Invest 94:722-30
Adams, D H; Russell, M E; Hancock, W W et al. (1993) Chronic rejection in experimental cardiac transplantation: studies in the Lewis-F344 model. Immunol Rev 134:5-19
Adams, D H; Wyner, L R; Karnovsky, M J (1993) Experimental graft arteriosclerosis. II. Immunocytochemical analysis of lesion development. Transplantation 56:794-9
Adams, D H; Wyner, L R; Karnovsky, M J (1993) Cardiac graft arteriosclerosis in the rat. Transplant Proc 25:2071-3

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