Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL043318-05
Application #
2220993
Study Section
Special Emphasis Panel (SRC (CD))
Project Start
1989-07-01
Project End
1995-04-30
Budget Start
1993-05-01
Budget End
1995-04-30
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Harvard University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Russell, M E; Hancock, W W; Wallace, A F et al. (1995) Modulation of inflammatory activation pathways in the Lewis-to-F-344 rat chronic cardiac rejection model. Transplant Proc 27:2100-4
Shin, Y T; Adams, D H; Wyner, L R et al. (1995) Intrathymic tolerance in the Lewis-to-F344 chronic cardiac allograft rejection model. Transplantation 59:1647-53
Russell, M E; Wallace, A F; Wyner, L R et al. (1995) Upregulation and modulation of inducible nitric oxide synthase in rat cardiac allografts with chronic rejection and transplant arteriosclerosis. Circulation 92:457-64
Russell, M E; Wallace, A F; Hancock, W W et al. (1995) Upregulation of cytokines associated with macrophage activation in the Lewis-to-F344 rat transplantation model of chronic cardiac rejection. Transplantation 59:572-8
Shin, Y T; Adams, D H; Wyner, L R et al. (1995) Intrathymic injection of donor splenocytes plus systemic antilymphocyte serum or antilymphocyte serum alone prolongs cardiac allograft survival and inhibits graft arteriosclerosis in the Lewis-to-F344 chronic rejection model. Transplant Proc 27:2112-4
Utans, U; Liang, P; Wyner, L R et al. (1994) Chronic cardiac rejection: identification of five upregulated genes in transplanted hearts by differential mRNA display. Proc Natl Acad Sci U S A 91:6463-7
Russell, M E; Utans, U; Wallace, A F et al. (1994) Identification and upregulation of galactose/N-acetylgalactosamine macrophage lectin in rat cardiac allografts with arteriosclerosis. J Clin Invest 94:722-30
Adams, D H; Wyner, L R; Karnovsky, M J (1993) Cardiac graft arteriosclerosis in the rat. Transplant Proc 25:2071-3
Adams, D H; Wyner, L R; Steinbeck, M J et al. (1993) Inhibition of graft arteriosclerosis by modulation of the inflammatory response. Transplant Proc 25:2092-4
Russell, M E; Adams, D H; Wyner, L R et al. (1993) Early and persistent induction of monocyte chemoattractant protein 1 in rat cardiac allografts. Proc Natl Acad Sci U S A 90:6086-90

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