Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL043794-05
Application #
2221183
Study Section
Pathology A Study Section (PTHA)
Project Start
1990-01-01
Project End
1995-12-31
Budget Start
1994-01-01
Budget End
1995-12-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Georgia
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
City
Athens
State
GA
Country
United States
Zip Code
30602
Greenspan, P; Yu, H; Mao, F et al. (1997) Cholesterol deposition in macrophages: foam cell formation mediated by cholesterol-enriched oxidized low density lipoprotein. J Lipid Res 38:101-9
Greenspan, P; Yu, H; Gutman, R L et al. (1996) Iron-ascorbate-phospholipid mediated modification of low density lipoprotein. Biochim Biophys Acta 1301:242-8
Ryu, B H; Mao, F W; Lou, P et al. (1995) Cholesteryl ester accumulation in macrophages treated with oxidized low density lipoprotein. Biosci Biotechnol Biochem 59:1619-22
Greenspan, P; Ryu, B H; Mao, F et al. (1995) Association of negatively-charged phospholipids with low-density lipoprotein (LDL) increases its uptake and the deposition of cholesteryl esters by macrophages. Biochim Biophys Acta 1257:257-64
Greenspan, P; Mao, F W; Ryu, B H et al. (1995) Advances in agarose gel electrophoresis of serum lipoproteins. J Chromatogr A 698:333-9
Greenspan, P; Gutman, R L (1994) Endocytosis of sulfatides by macrophages: relationship to the cellular uptake of phosphatidylserine. J Leukoc Biol 55:99-104
Lou, P; Gutman, R L; Mao, F W et al. (1994) Effects of phosphatidylserine on the oxidation of low density lipoprotein. Int J Biochem 26:539-45
Greenspan, P; Gutman, R L (1993) Detection by nile red of agarose gel electrophoresed native and modified low density lipoprotein. Electrophoresis 14:65-8
Greenspan, P; Lou, P (1993) Spectrofluorometric studies of nile red treated native and oxidized low density lipoprotein. Int J Biochem 25:987-91
Brown, W J; Sullivan, T R; Greenspan, P (1992) Nile red staining of lysosomal phospholipid inclusions. Histochemistry 97:349-54

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