Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL049575-04
Application #
2225670
Study Section
Special Emphasis Panel (SSS (M7))
Project Start
1993-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Siragy, H M; de Gasparo, M; Carey, R M (2000) Angiotensin type 2 receptor mediates valsartan-induced hypotension in conscious rats. Hypertension 35:1074-7
Siragy, H M; Carey, R M (1999) Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model. Hypertension 33:1237-42
Siragy, H M; Inagami, T; Ichiki, T et al. (1999) Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor. Proc Natl Acad Sci U S A 96:6506-10
Wang, Z Q; Millatt, L J; Heiderstadt, N T et al. (1999) Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension. Hypertension 33:96-101
Wang, Z Q; Moore, A F; Ozono, R et al. (1998) Immunolocalization of subtype 2 angiotensin II (AT2) receptor protein in rat heart. Hypertension 32:78-83
Carey, R M; Wang, Z Q; Siragy, H M et al. (1998) Renal dopamine production and release in the rat: a microdialysis study. Adv Pharmacol 42:873-6
Siragy, H M; Carey, R M (1997) The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats. J Clin Invest 100:264-9
Siragy, H M; Carey, R M (1997) The subtype 2 angiotensin receptor regulates renal prostaglandin F2 alpha formation in conscious rats. Am J Physiol 273:R1103-7
Ozono, R; O'Connell, D P; Wang, Z Q et al. (1997) Localization of the dopamine D1 receptor protein in the human heart and kidney. Hypertension 30:725-9
Ozono, R; Wang, Z Q; Moore, A F et al. (1997) Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney. Hypertension 30:1238-46

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