Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL050257-05
Application #
2028914
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1992-09-30
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Florida
Department
Genetics
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Klein, R L; McNamara, R K; King, M A et al. (1999) Generation of aberrant sprouting in the adult rat brain by GAP-43 somatic gene transfer. Brain Res 832:136-44
Klein, R L; Muir, D; King, M A et al. (1999) Long-term actions of vector-derived nerve growth factor or brain-derived neurotrophic factor on choline acetyltransferase and Trk receptor levels in the adult rat basal forebrain. Neuroscience 90:815-21
Klein, R L; Lewis, M H; Muzyczka, N et al. (1999) Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer. Brain Res 847:314-20
Pereira, D J; Muzyczka, N (1997) The adeno-associated virus type 2 p40 promoter requires a proximal Sp1 interaction and a p19 CArG-like element to facilitate Rep transactivation. J Virol 71:4300-9
Pereira, D J; Muzyczka, N (1997) The cellular transcription factor SP1 and an unknown cellular protein are required to mediate Rep protein activation of the adeno-associated virus p19 promoter. J Virol 71:1747-56
Peel, A L; Zolotukhin, S; Schrimsher, G W et al. (1997) Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters. Gene Ther 4:16-24
Gnatenko, D; Arnold, T E; Zolotukhin, S et al. (1997) Characterization of recombinant adeno-associated virus-2 as a vehicle for gene delivery and expression into vascular cells. J Investig Med 45:87-98
Ryan, J H; Zolotukhin, S; Muzyczka, N (1996) Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats. J Virol 70:1542-53
Fasbender, A J; Zabner, J; Welsh, M J (1995) Optimization of cationic lipid-mediated gene transfer to airway epithelia. Am J Physiol 269:L45-51
Einerhand, M P; Antoniou, M; Zolotukhin, S et al. (1995) Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transfer. Gene Ther 2:336-43