Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL053467-02
Application #
2231410
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1995-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Mueller, S; Cadenas, E; Schonthal, A H (2000) p21WAF1 regulates anchorage-independent growth of HCT116 colon carcinoma cells via E-cadherin expression. Cancer Res 60:156-63
Poderoso, J J; Carreras, M C; Schopfer, F et al. (1999) The reaction of nitric oxide with ubiquinol: kinetic properties and biological significance. Free Radic Biol Med 26:925-35
Laranjinha, J; Cadenas, E (1999) Redox cycles of caffeic acid, alpha-tocopherol, and ascorbate: implications for protection of low-density lipoproteins against oxidation. IUBMB Life 48:57-65
Cadenas, E; Sies, H (1998) The lag phase. Free Radic Res 28:601-9
Wu, R C; Hohenstein, A; Park, J M et al. (1998) Role of p53 in aziridinylbenzoquinone-induced p21waf1 expression. Oncogene 17:357-65
Qiu, X B; Schonthal, A H; Cadenas, E (1998) Anticancer quinones induce pRb-preventable G2/M cell cycle arrest and apoptosis. Free Radic Biol Med 24:848-54
Giulivi, C; Cadenas, E (1998) Extracellular activation of fluorinated aziridinylbenzoquinone in HT29 cells EPR studies. Chem Biol Interact 113:191-204
Giulivi, C; Cadenas, E (1998) The role of mitochondrial glutathione in DNA base oxidation. Biochim Biophys Acta 1366:265-74
Giulivi, C; Cadenas, E (1998) Oxidation of adrenaline by ferrylmyoglobin. Free Radic Biol Med 25:175-83
Giulivi, C; Forlin, A; Bellin, S et al. (1998) Reactions of halogen-substituted aziridinylbenzoquinones with glutathione. Formation of diglutathionyl conjugates and semiquinones. Chem Biol Interact 108:137-54

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