Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL055556-02
Application #
2234156
Study Section
Special Emphasis Panel (ZHL1-CSR-K (M1))
Project Start
1995-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Bloodcenter of Wisconsin, Inc.
Department
Type
DUNS #
City
Milwaukee
State
WI
Country
United States
Zip Code
53233
Erickson, Yasuko O; Samia, Noelle I; Bedell, Bruce et al. (2009) Elevated procalcitonin and C-reactive protein as potential biomarkers of sepsis in a subpopulation of thrombotic microangiopathy patients. J Clin Apher 24:150-4
Raife, Thomas J; Cao, Wenjing; Atkinson, Bonnie S et al. (2009) Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site. Blood 114:1666-74
Mosesson, M W; Hernandez, I; Raife, T J et al. (2007) Plasma fibrinogen gamma'chain content in the thrombotic microangiopathy syndrome. J Thromb Haemost 5:62-9
Raife, Thomas J; Friedman, Kenneth D; Dwyre, Denis M (2006) The pathogenicity of von Willebrand factor in thrombotic thrombocytopenic purpura: reconsideration of treatment with cryopoor plasma. Transfusion 46:74-9
Raife, Thomas; Friedman, Kenneth D; Fenwick, Brad (2004) Lepirudin prevents lethal effects of Shiga toxin in a canine model. Thromb Haemost 92:387-93
Raife, Thomas; Atkinson, Bonnie; Montgomery, Robert et al. (2004) Severe deficiency of VWF-cleaving protease (ADAMTS13) activity defines a distinct population of thrombotic microangiopathy patients. Transfusion 44:146-50
Mauro, Michael; Zlatopolskiy, Andrey; Raife, Thomas J et al. (2004) Thienopyridine-linked thrombotic microangiopathy: association with endothelial cell apoptosis and activation of MAP kinase signalling cascades. Br J Haematol 124:200-10
Raife, Thomas J; Lentz, Steven R; Atkinson, Bonnie S et al. (2002) Factor V Leiden: a genetic risk factor for thrombotic microangiopathy in patients with normal von Willebrand factor-cleaving protease activity. Blood 99:437-42
Raife, T; Montgomery, R (2001) New aspects in the pathogenesis and treatment of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. Rev Clin Exp Hematol 5:236-61; discussion 311-2
Raife, T J; Montgomery, R R (2000) von Willebrand factor and thrombotic thrombocytopenic purpura. Curr Opin Hematol 7:278-83

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