Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL059225-05
Application #
6691071
Study Section
Alcohol and Toxicology Subcommittee 4 (ALTX)
Program Officer
Massicot-Fisher, Judith
Project Start
1999-04-01
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
5
Fiscal Year
2004
Total Cost
$256,229
Indirect Cost
Name
University of Louisville
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
057588857
City
Louisville
State
KY
Country
United States
Zip Code
40292
Kang, Y James (2011) Copper and homocysteine in cardiovascular diseases. Pharmacol Ther 129:321-31
Xie, Huiqi; Kang, Y James (2009) Role of copper in angiogenesis and its medicinal implications. Curr Med Chem 16:1304-14
Feng, Wenke; Ye, Fei; Xue, Wanli et al. (2009) Copper regulation of hypoxia-inducible factor-1 activity. Mol Pharmacol 75:174-82
Purohit, Vishnudutt; Bode, J Christian; Bode, Christiane et al. (2008) Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. Alcohol 42:349-61
Zhou, Yang; Jiang, Youchun; Kang, Y James (2008) Copper reverses cardiomyocyte hypertrophy through vascular endothelial growth factor-mediated reduction in the cell size. J Mol Cell Cardiol 45:106-17
Lynes, Michael A; Kang, Y James; Sensi, Stefano L et al. (2007) Heavy metal ions in normal physiology, toxic stress, and cytoprotection. Ann N Y Acad Sci 1113:159-72
Feng, Wenke; Wang, Yuehui; Cai, Lu et al. (2007) Metallothionein rescues hypoxia-inducible factor-1 transcriptional activity in cardiomyocytes under diabetic conditions. Biochem Biophys Res Commun 360:286-9
Kang, Y James (2007) Antioxidant defense against anthracycline cardiotoxicity by metallothionein. Cardiovasc Toxicol 7:95-100
Merten, Kevyn E; Jiang, Youchun; Kang, Y James (2007) Zinc inhibits doxorubicin-activated calcineurin signal transduction pathway in H9c2 embryonic rat cardiac cells. Exp Biol Med (Maywood) 232:682-9
Zhou, Yang; Jiang, Youchun; Kang, Y James (2007) Copper inhibition of hydrogen peroxide-induced hypertrophy in embryonic rat cardiac H9c2 cells. Exp Biol Med (Maywood) 232:385-9

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