Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL059590-02
Application #
6363551
Study Section
Surgery and Bioengineering Study Section (SB)
Program Officer
Sopko, George
Project Start
2000-03-01
Project End
2004-02-28
Budget Start
2001-05-15
Budget End
2002-02-28
Support Year
2
Fiscal Year
2001
Total Cost
$125,360
Indirect Cost
Name
Dartmouth College
Department
Surgery
Type
Schools of Medicine
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
Brown, David J; Rzucidlo, Eva M; Merenick, Bethany L et al. (2005) Endothelial cell activation of the smooth muscle cell phosphoinositide 3-kinase/Akt pathway promotes differentiation. J Vasc Surg 41:509-16
Martin, Kathleen A; Rzucidlo, Eva M; Merenick, Bethany L et al. (2004) The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation. Am J Physiol Cell Physiol 286:C507-17
Mulligan-Kehoe, Mary Jo; Kleinman, Hynda K; Drinane, Mary et al. (2002) A truncated plasminogen activator inhibitor-1 protein blocks the availability of heparin-binding vascular endothelial growth factor A isoforms. J Biol Chem 277:49077-89
Proia, Richard R; Nelson, Peter R; Mulligan-Kehoe, Mary Jo et al. (2002) The effect of endothelial cell overexpression of plasminogen activator inhibitor-1 on smooth muscle cell migration. J Vasc Surg 36:164-71
Mulligan-Kehoe, M J; Wagner, R; Wieland, C et al. (2001) A truncated plasminogen activator inhibitor-1 protein induces and inhibits angiostatin (kringles 1-3), a plasminogen cleavage product. J Biol Chem 276:8588-96