Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL060746-05
Application #
6692672
Study Section
Lung Biology and Pathology Study Section (LBPA)
Program Officer
Peavy, Hannah H
Project Start
1999-04-01
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
5
Fiscal Year
2004
Total Cost
$382,500
Indirect Cost

  Institution

Name
Fox Chase Cancer Center
Department
Type
DUNS #
073724262
City
Philadelphia
State
PA
Country
United States
Zip Code
19111

  Publications

Robb, Victoria A; Astrinidis, Aristotelis; Henske, Elizabeth P (2006) Frequent [corrected] hyperphosphorylation of ribosomal protein S6 [corrected] in lymphangioleiomyomatosis-associated angiomyolipomas. Mod Pathol 19:839-46
Crino, Peter B; Nathanson, Katherine L; Henske, Elizabeth Petri (2006) The tuberous sclerosis complex. N Engl J Med 355:1345-56
Yu, Jane; Astrinidis, Aristotelis; Howard, Sharon et al. (2004) Estradiol and tamoxifen stimulate LAM-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways. Am J Physiol Lung Cell Mol Physiol 286:L694-700
Astrinidis, Aristotelis; Henske, Elizabeth Petri (2004) Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex. J Child Neurol 19:710-5
Karbowniczek, Magdalena; Cash, Timothy; Cheung, Mitchell et al. (2004) Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent. J Biol Chem 279:29930-7
Karbowniczek, Magdalena; Astrinidis, Aristotelis; Balsara, Binaifer R et al. (2003) Recurrent lymphangiomyomatosis after transplantation: genetic analyses reveal a metastatic mechanism. Am J Respir Crit Care Med 167:976-82
Karbowniczek, Magdalena; Yu, Jane; Henske, Elizabeth Petri (2003) Renal angiomyolipomas from patients with sporadic lymphangiomyomatosis contain both neoplastic and non-neoplastic vascular structures. Am J Pathol 162:491-500
Astrinidis, Aristotelis; Cash, Timothy P; Hunter, Deborah S et al. (2002) Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration. Oncogene 21:8470-6
Yu, J; Astrinidis, A; Henske, E P (2001) Chromosome 16 loss of heterozygosity in tuberous sclerosis and sporadic lymphangiomyomatosis. Am J Respir Crit Care Med 164:1537-40
Strizheva, G D; Carsillo, T; Kruger, W D et al. (2001) The spectrum of mutations in TSC1 and TSC2 in women with tuberous sclerosis and lymphangiomyomatosis. Am J Respir Crit Care Med 163:253-8

Showing the most recent 10 out of 13 publications