This five-year project, titled """"""""Go Girls II"""""""", will develop and test an intervention for overweight 12-16 year old African American adolescents and their parents. The project will be conducted in two stages: 1) Formative Research and Pilot Testing (Years 0-1.5); and 2) Randomized Field Trial (Years 1.5-5). The Project will be conducted in middle and upper socioeconomic Black churches in the Atlanta Metropolitan area. GG II builds on several prior studies conducted by our group including Eat for Life, Go Girls I, Keepin' It Real, and Know Your Body. The intervention, which will undergo extensive pilot testing and formative evaluation, will include group nutrition and physical activity sessions conducted at churches. Each session will comprise three components; 1) experiential, interactive behavioral nutrition and physical education activity; 2) 30-45 minutes of physical activity; and 3) preparation and consumption of low-fat, portion controlled meals and snacks. Intervention families will receive nutrition education video materials and parents will receive an exercise audio tape. For some sessions, children and parents will meet jointly, while for others, break out sessions will be used. Target behaviors for the intervention include: 1) increased fruit and vegetable intake; 2) decreased fat intake; 3) decreased fast food intake; 4) decreased television viewing; and S) increased physical activity. During Stage 1 formative research, activities from our GG I intervention, which targeted low income overweight African American adolescents, will be adapted to a middle/upper income African American population. Stage 1 will culminate in a 12-week pilot of the intervention in two churches. For the Stage 2 field trial 6-9 churches (25-30 families recruited per church) will be randomly assigned to treatment or comparison condition. Participants will be tracked for one year. Incentives will be used to enhance recruitment and retention. The primary outcome will be adiposity, assessed by BMI and Dual Energy X-ray Absorptiometry. Secondary outcomes include; blood pressure, blood lipids, serum insulin, cardiovascular fitness, diet (24hr recalls and FFQ), physical activity (7-day recall), and cognitive measures (e.g., attitudes and efficacy). Safety will be evaluated using eating practices and growth curve data. The study employs a nested cohort design, with churches, rather than individuals assigned to condition. To control for cluster randomization effects in outcome analyses, we will utilize SAS/PROC MIXED, with church as the unit of analysis.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL062659-03
Application #
6490772
Study Section
Special Emphasis Panel (ZRG1-SNEM-1 (01))
Program Officer
Obarzanek, Eva
Project Start
2000-01-15
Project End
2003-12-31
Budget Start
2002-01-01
Budget End
2002-12-31
Support Year
3
Fiscal Year
2002
Total Cost
$747,986
Indirect Cost
Name
Emory University
Department
Psychology
Type
Schools of Public Health
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Zhou, Beiyun; Ann, David K; Flodby, Per et al. (2008) Rat aquaporin-5 4.3-kb 5'-flanking region differentially regulates expression in salivary gland and lung in vivo. Am J Physiol Cell Physiol 295:C111-20
Zhou, Beiyun; Francis, Tricia A; Yang, Hui et al. (2008) GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1. Am J Physiol Cell Physiol 295:C1141-50
Patel, Leena N; Uchiyama, Tomomi; Kim, Kwang-Jin et al. (2008) Molecular and functional expression of multidrug resistance-associated protein-1 in primary cultured rat alveolar epithelial cells. J Pharm Sci 97:2340-9
Zhou, Beiyun; Zhong, Qian; Minoo, Parviz et al. (2008) Foxp2 inhibits Nkx2.1-mediated transcription of SP-C via interactions with the Nkx2.1 homeodomain. Am J Respir Cell Mol Biol 38:750-8
Flodby, Per; Zhou, Beiyun; Ann, David K et al. (2007) Conserved elements within first intron of aquaporin-5 (Aqp5) function as transcriptional enhancers. Biochem Biophys Res Commun 356:26-31
Zhou, Beiyun; Ann, David K; Li, Xian et al. (2007) Hypertonic induction of aquaporin-5: novel role of hypoxia-inducible factor-1alpha. Am J Physiol Cell Physiol 292:C1280-90
Resnicow, Ken; McCarty, Frances; Blissett, Dhana et al. (2003) Validity of a modified CHAMPS physical activity questionnaire among African-Americans. Med Sci Sports Exerc 35:1537-45
Resnicow, Ken; DiIorio, Colleen; Soet, Johanna E et al. (2002) Motivational interviewing in health promotion: it sounds like something is changing. Health Psychol 21:444-51
Baskin, M L; Resnicow, K; Campbell, M K (2001) Conducting health interventions in black churches: a model for building effective partnerships. Ethn Dis 11:823-33
Baskin, M L; Ahluwalia, H K; Resnicow, K (2001) Obesity intervention among African-American children and adolescents. Pediatr Clin North Am 48:1027-39